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Journal of Renal Nutrition
Volume 11, Issue 4
, Pages 181-182
, October 2001
The protein metabolite theory as a mechanism for the progression of renal failure
References
- . Indoxyl sulfate, a circulating uremic toxin, stimulates the progression of glomerular sclerosis. J Lab Clin Med. 1994;124:96–104
- . Progression of glomerular sclerosis in experimental uremic rats by administration of indole, a precursor of indoxyl sulfate. Am J Nephrol. 1994;14:207–212
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Indoxyl sulfate increases the gene expressions of TGF-β1, TIMP-1 and proα1(l) collagen in kidneys of uremic rats.
Kidney Int. 1997;52(suppl 62):S15–S22
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Indoxyl sulfate and progression of renal failure: Effects of a low-protein diet and oral sorbent on indoxyl sulfate production in uremic rats and undialyzed uremic patients.
Miner Electrol Metab. 1997;23:179–194
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The protein metabolite hypothesis, a model for the progression of renal failure: An oral sorbent lowers indoxyl sulfate levels in undialyzed uremic patients.
Kidney Int. 1997;52(Suppl 62):S23–S28
- An oral sorbent reduces overload of indoxyl sulfate and gene expression of TGF-β1 in uremic rat kidneys. Nephrol Dial Transplant. 2000;15:1773–1781
PII: S1051-2276(01)30549-6
doi: 10.1016/S1051-2276(01)30549-6
© 2001 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.
Next »
Journal of Renal Nutrition
Volume 11, Issue 4
, Pages 181-182
, October 2001

