Journal of Renal Nutrition
Volume 11, Issue 1 , Pages 9-15 , January 2001

Can a Nutrition Intervention Improve Albumin Levels Among Hemodialysis Patients? A Pilot Study

  • Janeen B. Leon, MS, RD, LD

      Affiliations

    • Division of Nephrology and Center for Health Care Research and Policy, MetroHealth Medical Center, Cleveland, OH.
    • ,
  • Angela D. Majerle, RD

      Affiliations

    • Department of Nutrition Services, MetroHealth Medical Center, Cleveland, OH.
    • ,
  • Jeanette A. Soinski, RD, CS, LD

      Affiliations

    • Centers for Dialysis Care, Cleveland, OH.
    • ,
  • Irving Kushner, MD

      Affiliations

    • Division of Rheumatology, MetroHealth Medical Center, Cleveland, OH.
    • Department of Medicine, Case Western Reserve University, Cleveland, OH.
    • ,
  • Punam Ohri-Vachaspati, PhD, RD

      Affiliations

    • Ohio State University Extension, Cleveland Heights, OH.
    • ,
  • Ashwini R. Sehgal, MD

      Affiliations

    • Division of Nephrology and Center for Health Care Research and Policy, MetroHealth Medical Center, Cleveland, OH.
    • Department of Medicine, Case Western Reserve University, Cleveland, OH.
    • Center for Biomedical Ethics, Case Western Reserve University. Cleveland, OH.
    • Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland. OH.
    • Corresponding Author InformationAddress reprint requests to Ashwini R. Sehgal, MD, Division of Nephrology, 2500 MetroHealth Dr, MetroHealth Medical Center, Cleveland, OH 44109-1998.

References 

  1. Lowrie EG, Lew NL. Death risk in hemodialysis patients: The predictive value of commonly measured variables and an evaluation of death rate differences between facilities. Am J Kidney Dis. 1990;15:458–482
  2. Health Care Financing Administration. 1999 Annual Report, ESRD Clinical Measures Performance Project. Baltimore, MD, Department of Health and Human Services, Health Care Financing Administration, Office of Clinical Standards and Quality, December 1999
  3. Acchiardo SR, Moore LW, Latour PA. Malnutrition as the main factor in morbidity and mortality of hemodialysis patients. Kidney Int. 1983;24(suppl):S199–S203
  4. Bergstrom J. Nutrition and mortality in hemodialysis. J Am Soc Nephrol. 1995;6:1329–1341
  5. Hakim RM, Levin N. Malnutrition in hemodialysis patients. Am J Kidney Dis. 1993;21:125–137
  6. Ikizler TA, Hakim RM. Nutrition in end-stage renal disease. Kidney lnt. 1996;50:343–357
  7. Kopple JD. Effect of nutrition on morbidity and mortality in maintenance dialysis patients. Am J Kidney Dis. 1994;24:1002–1009
  8. Chertow GM, Lazarus JM. Malnutrition as a risk factor for morbidity and mortality in maintenance dialysis patients. In:  Kopple JD,  Massry SG editor. Nutritional Management of Renal Disease. Baltimore, MD: Williams & Wilkins; 1997;p. 257–276
  9. Ikizler TA, Wingard RL, Hakim RM. Interventions to treat malnutrition in dialysis patients: The role of dose of dialysis, intradialytic parenteral nutrition, and growth hormone. Am J Kidney Dis. 1995;26:256–265
  10. Boccanfuso JA, Hutton M, McAilister B. The effect of megestrol acetate on nutritional parameters in a dialysis population. J Ren Nutr. 2000;10:36–43
  11. Chazot C, Shahmir E, Matias B, et al. Dialytic nutrition: Provision on amino acids in dialysate during hemodialysis. Kidney Int. 1997;52:1663–1670
  12. Johansen KL, Mulligan K, Schambelan M. Anabolic effects of nandrolone decanoate in patients receiving dialysis: A randomized controlled trial. JAMA. 1999;281:1275–1281
  13. Beutler KT, Park GK, Wilkowski MJ. Effect of oral supplementation on nutrition indicators in hemodialysis patients. J Ren Nutr. 1997;7:77–82
  14. Engel B, Kon P, Raftery MJ. Strategies to identify and correct malnutrition in hemodialysis patients. J Ren Nutr. 1995;5:62–66
  15. Kushner I. The phenomenon of the acute phase response. Ann N Y Acad Sci. 1982;389:39–48
  16. Gabay C, Kushner I. Acute-phase proteins and other systemic responses to inflammation. N Engl J Med. 1999;340:448–454
  17. Ikizler TA, Wingard RL, Harvell J, et al. Association of morbidity with markers of nutrition and inflammation in chronic hemodialysis patients: A prospective study. Kidney Int. 1999;55:1945–1951
  18. Kaysen GA, Stevenson FT, Depner TA. Determinants of albumin concentration in hemodialysis patients. Am J Kidney Dis. 1997;29:658–668
  19. Yeun JY, Kaysen GA. Factors influencing serum albumin in hemodialysis patients. Am J Kidney Dis. 1998;32(suppl):S118–S125
  20. Sehgal AR, O'Rourke SG, Snyder C. Patient assessments of adequacy of dialysis and protein nutrition. Am J Kidney Dis. 1997;30:514–520
  21. Sehgal AR, Leon J, Soinski JA. Barriers to adequate protein nutrition among hemodialysis patients. J Ren Nutr. 1998;8:179–187
  22. Ohri-Vachaspati P, Sehgal AR. Correlates of poor appetite among hemodialysis patients. J Ren Nutr. 1999;9:182–185
  23. Rimer BK, Orleans CT. Tailoring smoking cessation for older adults. Cancer. 1994;74(suppl):S2051–S2054
  24. Campbell MK, DeVellis BM, Strecher VJ, et al. Improving dietary behavior: The effectiveness of tailored messages in primary care settings. Am J Public Health. 1994;84:783–787
  25. Hakim RM, Depner TA, Parker TF. Adequacy of hemodialysis. Am J Kidney Dis. 1992;20:107–123
  26. Morley JJ, Kushner I. Serum C-reactive protein levels in disease. Ann N Y Acad Sci. 1982;389:406–418
  27. Macy EM, Hayes TE, Tracy RP. Variability in the measurement of C-reactive protein in healthy subjects: Implications for reference intervals and epidemiological applications. Clin Chem. 1997;43:52–58
  28. Chertow GM. Modality-specific nutrition support in ESRD: Weighing the evidence. Am J Kidney Dis. 1999;33:193–197
  29. Foulks CJ. An evidence-based evaluation of intradialytic parenteral nutrition. Am J Kidney Dis. 1999;33:186–192
  30. Kopple JD. Therapeutic approaches to malnutrition in chronic dialysis patients: The different modalities of nutritional support. Am J Kidney Dis. 1999;33:180–185
  31. Ohri-Vachaspati P, Sehgal AR. Quality of life implications of inadequate protein nutrition among hemodialysis patients. J Ren Nutr. 1999;9:9–13

 Supported by grant number DK51472 and DK54178 from the National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda. MD, and the Leonard C. Rosenberg Renal Research Fonndation, Cleveland, OH.

PII: S1051-2276(01)79890-1

Journal of Renal Nutrition
Volume 11, Issue 1 , Pages 9-15 , January 2001

Article Tools