Journal of Renal Nutrition
Volume 13, Issue 1 , Pages 47-51 , January 2003

Oral use of iron with vitamin C in hemodialyzed patients

  • Miroslav Mydlík, Prof, MD, DSc

      Affiliations

    • Professor of Internal Medicine and Nephrology, Chief of Nephrological Clinic, University Hospital of L.Pasteur, Košice, Slovak Republic
    • ,
  • Katarína Derzsiová, Ing

      Affiliations

    • Nephrological Clinic, University Hospital of L.Pasteur, Košice, Slovak Republic
    • ,
  • Ján Boldizsár, MD

      Affiliations

    • Internal Clinic, Dialysis Unit, District Hospital, Nové Zámky, Slovak Republic
    • ,
  • Mária Hríbiková, Ing

      Affiliations

    • Department of Clinical Biochemistry, District Hospital, Nové Zámky, Slovak Republic
    • ,
  • Jozefína Petrovičová, RNDr, PhD

      Affiliations

    • Institute of Medical Informatics, Medical Faculty of P.J. Šafárik University, Košice, Slovak Republic

References 

  1. Eschbach JW, Egrie JC, Downing MR, et al.  Correction of the anemia of end-stage renal disease with recombinant human erythropoietin. Results of a combined phase I and II clinical trial. N Engl J Med. 1987;316:73–78
  2. Hörl WH. Is there a role for adjuvant therapy in patients being treated with epoetin?. Nephrol Dial Transplant. 1999;14:50–60 (suppl)
  3. Mydlík M, Derzsiová K, źemberová E. Metabolism of vitamin B6 and its requirements in chronic renal failure. Kidney Int. 1997;52:56–59 (suppl)
  4. Fishbane S, Frei GI, Maesaka J. Reduction in recombinant human erythropoietin doses by the use of chronic intravenous iron supplementation. Am J Kidney Dis. 1995;26:41–46
  5. Tarng GC, Wei YH, Huang TP, et al.  Intravenous ascorbic acid as an adjuvant therapy for recombinant erythropoietin in haemodialysis patients with hyperferritinemia. Kidney Int. 1999;55:2477–2486
  6. Tonbul HZ, Kaya H, Selcuk NY, et al.  The importance of serum transferrin receptor level in the diagnosis of functional iron deficiency due to recombinant human erythropoietin treatment in haemodialysis patients. Int Urol Nephrol. 1998;30:645–651
  7. Macdougall IC. Metabolic adjuvants to erythropoietin therapy. Miner Electrolyte Metab. 1999;25:357–364
  8. Macdougall IC, Tucker B, Thompson J, et al.  A randomized controlled study of iron supplementation in patients treated with erythropoietin. Kidney Int. 1996;50:1694–1699
  9. Wingard RL, Parker RA, Ismail N, et al.  Efficacy of oral iron therapy in patients receiving recombinant human erythropoietin. Am J Kidney Dis. 1995;25:433–439
  10. Tarng DC, Huang TP, Chen TW, et al.  Erythropoietin hyporesponsiveness: From iron deficiency to iron overload. Kidney Int. 1999;55(suppl):107–108
  11. Hallberg L, Brune M, Rossander L. The role of vitamin C in iron absorption. Int J Vitam Nutr Res. 1989;30(suppl):103–108
  12. Pru C, Ealton J, Kjellstrand C. Vitamin C intoxication and hyperoxalemia in chronic hemodialysis patients. Nephron. 1985;39:112–116
  13. Ono K. Secondary hyperoxalemia caused by vitamin C supplementation in regular hemodialysis patients. Clin Nephrol. 1986;26:239–243
  14. Tomson CR, Channon SM, Ward MK, et al.  Plasma oxalate concentration, oxalate clearance and cardiac function in patients receiving haemodialysis. Nephrol Dial Transplant. 1989;4:792–799
  15. Rivers JM. Safety of high-level vitamin C ingestion. Int J Vitam Nutr Res. 1989;30(suppl):95–102
  16. Makoff R. Vitamins replacement therapy in renal failure patients. Miner Electrolyte Metab. 1999;25:349–351
  17. Caraway WT. Macro and micro methods for the determination of serum iron and iron-binding capacity. Clin Chem. 1963;9:188–199
  18. In: ed 6.  Hořejší J editors. The Fundamentals of Chemical Investigation in Medicine. Prague: Státní Zdravotnícké Nakladatelství; 1964;
  19. Rolton HA, McConnel KN, Modi KS, et al.  A simple, rapid assay for plasma oxalate in uraemic patients using oxalate oxidase, which is free from vitamin C interference. Clin Chim Acta. 1989;182:247–254

☆ Supported in part by grant KLV 48/1997 from the Ministry of Health of Slovak Republic and EGIS Slovakia, Nové Zámky, Slovak Republic.

☆☆ Address reprint requests to Professor M.Mydlík, MD, DSc, Nephrological Clinic, University Hospital of L.Pasteur, Rastislavova 43, 041 90 Košice, Slovak Republic.

PII: S1051-2276(02)13408-X

doi: 10.1053/jren.2003.50007

Journal of Renal Nutrition
Volume 13, Issue 1 , Pages 47-51 , January 2003

Article Tools

* Image Usage & Resolution