Journal of Renal Nutrition
Volume 15, Issue 2 , Pages 225-230 , April 2005

L-carnitine infusions may suppress serum C-reactive protein and improve nutritional status in maintenance hemodialysis patients

  • Vincenzo Savica, MD

      Affiliations

    • University of Messina, Messina, Italy
    • Nephrology and Dialysis Unit, Papardo Hospital, Messina, Italy
    • ,
  • Domenico Santoro, MD

      Affiliations

    • University of Messina, Messina, Italy
    • Corresponding Author InformationAddress reprint requests to Domenico Santoro, University of Messina, Division of Nephrology, c.da Conte Coop. Sperone is. 3/E, 98168 Messina, Italy
    • ,
  • Giampiero Mazzaglia, MD

      Affiliations

    • Health Search, Italian College of General Practitioners, Messina, Italy
    • ,
  • Franco Ciolino, MD

      Affiliations

    • Nephrology and Dialysis Unit, Papardo Hospital, Messina, Italy
    • ,
  • Paolo Monardo, MD

      Affiliations

    • Nephrology and Dialysis Unit, Papardo Hospital, Messina, Italy
    • ,
  • Menotti Calvani, MD

      Affiliations

    • Scientific Department, Sigma-Tau, Rome, Italy
    • ,
  • Guido Bellinghieri, MD

      Affiliations

    • University of Messina, Messina, Italy
    • ,
  • Joel D. Kopple, MD

      Affiliations

    • Division of Nephrology and Hypertension and Research and Education Institute, Harbor-UCLA Medical Center, Torrance, CA, USA and the David Geffen School of Medicine and the School of Public Health at UCLA, Los Angeles, CA, USA

References 

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  10. Owen WF , Lew NL , Liu Y , et al.   The urea reduction ratio and serum albumin concentration as predictor of mortality in patients undergoing hemodialysis . N Engl J Med . 1993;329:1001–1006
  11. Kaysen GA . Biological basis of hypoalbuminemia in ESRD . J Am Soc Nephrol . 1998;9:2368–2376
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  13. Guarnieri G , Situlin R , Biolo G . Carnitine metabolism in uremia . Am J Kidney Dis . 2001;38(suppl 1):S63–S71
  14. Kopple JD , Peiyuan-Qing D . Effect of L-carnitine on nitrogen balance in CAPD patients . J Am Soc Nephrol . 1998;10:P264A; (abstr)
  15. Kouttab NM , De Simone C . Modulation of cytokine production by carnitine . Mediators of Inflammation . 1993;2:S25–S28
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  17. De Simone C , Tzantzoglou S , Jirillo E , et al.   L-carnitine deficiency in AIDS patients . AIDS . 1991;6:203–205
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  20. Maguire GA , Price CP . Bromocresol purple method for serum albumin gives falsely low values in patients with renal insufficiency . Clin Chim Acta . 1986;155:83–88
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  26. Savica V , Bonomini M , Calvani M , et al.   Ruolo della Carnitina nell’uremia . Giorn Ital Nefrol . 2001;18(suppl 17):92–95
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  28. Savica V , Bellinghieri G , Di Stefano C , et al.   Plasma and muscle carnitine levels in hemodialysis patients with morphological-ultrastructural examination of muscle samples . Nephron . 1983;35:232–236
  29. Bellinghieri G , Savica V , Mallamace A , et al.   Correlation between increased serum and tissue L-carnitine levels and improved muscle symptoms in hemodialyzed patients . Am J Clin Nutr . 1983;38:523–531

PII: S1051-2276(04)00250-X

doi: 10.1053/j.jrn.2004.10.002

Journal of Renal Nutrition
Volume 15, Issue 2 , Pages 225-230 , April 2005

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