Renal dietitians have been raging a war on phosphorus since the nephrology community discovered its harmful effects. Historically, we hoped to protect the patients from renal osteodystrophy associated with chronic hyperphosphatemia. Now, we try to protect them from the systemic effects, such as cardiac calcification, associated with elevated serum phosphorus levels.1
With the introduction of the National Kidney Foundation’s Kidney Disease Outcomes and Quality Initiative Clinical Practice Guidelines for Bone Metabolism and Disease in Chronic Kidney Disease, there has been an increased focus on achieving serum calcium, phosphorus, CaxP product, and parathyroid hormone goals. Medications such as sevelamer hydrochloride and calcimimetic agents have helped us to reach our calcium and parathyroid hormone goals, however, hyperphosphatemia continues to be an ongoing problem.
To combat the problem of hyperphosphatemia, dietitians have emphasized adherence to phosphate binder prescriptions and maintenance of a low-phosphorus diet. In addition to the standard advice to avoid dairy products and legumes, we also advised patients regarding low-phosphorus protein foods. We continue to encourage our patients to avoid colas and “pepper”-style beverages and rallied behind root beer, iced teas, and other “clear” beverages. They were considered safe. That is, until now…
Phosphorus additives
As Americans continue to demand high-quality convenience food, food-processing practices have stepped up the use of phosphorus additives to ensure the quality and flavor that Americans have come to expect. The most notable products using phosphorus additives are restructured meats (chicken nuggets and hotdogs), processed and spreadable cheeses, instant products (puddings and sauces), refrigerated bakery products, and beverages.2
In 1990, phosphorus additives contributed an estimated 470 mg of phosphorus per day to the American diet.2 With the surge in the popularity of these new foods, additives could now contribute up to 1,000 mg of phosphorus per day depending on an individual’s food choices.3
What makes this problem unique to the renal community?
These phosphorus additives are highly absorbable. In a typical mixed diet of grains, meat, and dairy, only 60% of the dietary phosphorus is absorbed, whereas phosphoric acid and various polyphosphates and pyrophosphates are almost 100% absorbed.4 Diets higher in these inorganic salts will result in higher phosphorus absorption.
Identifying these new higher-phosphorus foods can be challenging. Manufacturers are no longer required to list the phosphorus content on the food label. If the manufacturer does analyze the product for phosphorus, it is sometimes classified as proprietary information. Often the analysis is not readily accessible to customer service representatives, who must submit the request for information to one or two different departments. Then there is no guarantee that the company can locate the information.
Another challenge is the practice of products being affiliated with one company and manufactured, packaged, and distributed by another company. For example, Country Time Lemonade is considered a Kraft-brand food, but some Country Time Lemonade products are manufactured and distributed through Dr. Pepper/7-Up. Finally, each company formulates its products differently, and within each product, the individual delivery packages may be formulated differently. For instance, the ingredients in a bottled iced tea may be different than the same brand of canned iced tea.
Table 1 presents the sodium, potassium, and phosphorus content of most commonly consumed beverages. You may be surprised to see that Hire’s root beer contains phosphorus, Diet Coke has less phosphorus than any other diet cola, and a 12-oz can of Nestea Cool iced tea has more phosphorus than 4 oz of milk!
Table 1.
Nutrition Analysis of Selected Beverages
Product
Sodium (mg)
Potassium (mg)
Phosphorus (mg)
A&W
A&W Cream Soda
45
0.6
0.6
Diet A&W Cream Soda
70
0.4
0.1
A&W Root Beer
45
0.5
0.7
Diet A&W Root Beer
70
0.2
0
Canada Dry
Club Soda
90
0.2
0.2
Collins Mixer
28
54
3
Cranberry Ginger Ale
28
0.4
0.5
Ginger Ale
75
0.2
0.1
Diet Cranberry Ginger Ale
40
0.3
0.5
Seltzer
15
0
Tonic Water
25
0.3
0.4
Diet Tonic Water
50
0.1
0
Crush
Orange
45
0.5
0.5
Diet Rite
Diet Rite Cola
0
17
41
Diet Rite Black Cherry
0
56
0.1
Diet Rite Kiwi Strawberry
0
19
0
Diet Rite Red Raspberry
0
44
0
Diet Rite Tangerine
0
32
0
Diet Rite White Grape
0
17
0
Diet Rite Golden Peach
0
47
0
Dr. Pepper
Dr. Pepper
55
0.4
45
Diet Dr. Pepper
55
0.1
44
Caffeine-Free Dr. Pepper
55
0.4
45
Caffeine-Free Diet Dr. Pepper
55
0.1
44
Red Fusion
55
0.4
32
Hawaiian Punch
Fruit Juicy
170
45
173
Green Berry Rush
170
44
173
Hire’s
Root Beer
70
0.5
20
Diet Root Beer
100
0.2
20
RC
RC Cola
50
0.4
52
Diet RC Cola
45
45
31
RC Cherry Cola
50
0.6
52
RC Caffeine-Free Cola
45
0.5
52
Schweppes
Bitter Lemon (10-oz serving)
55
12
1
Collins Mixer
25
0.2
0
Club Soda
105
0.5
0.4
Ginger Ale
40
0.3
0.3
Diet Ginger Ale
90
0.1
0
7-Up
7-Up
75
0.6
0.6
7-Up Diet
45
77
0.1
Cherry 7-Up
40
30
0.5
Diet Cherry 7-Up
45
44
0
Squirt
Squirt
25
5
0.8
Diet Squirt
25
12
1
Ruby Red Squirt
25
7
1
Diet Ruby Red Squirt
30
7
0.7
Sundrop
Sundrop
30
7
1
Diet Sundrop
100
51
4
Cherry Sundrop
30
7
0.7
Caffeine-Free Sundrop
30
7
1
Sunkist
Orange
45
0.2
0.2
Diet Orange
100
0.1
0
Vernor’s
Vernor’s
25
0.3
0.5
Diet Vernor’s
15
0.1
0
Welch’s
Grape
55
3
0.8
Strawberry
45
0.5
0.6
Fruit Punch
45
0.5
0.6
Country Time Lemonade
Country Time Lemonade
105
10
0.4
Pepsi
Pepsi
35
0
53
Caffeine-Free Pepsi
35
10
53
Pepsi Blue
35
62
33
Pepsi One
45
30
55
Diet Pepsi
35
30
41
Diet Caffeine-Free Pepsi
35
30
41
Pepsi Twist
40
79
54
Diet Pepsi Twist
40
46
41
Pepsi Vanilla
40
0
43
Diet Pepsi Vanilla
40
0
43
Wild Cherry
35
0
53
Wild Cherry Diet
40
56
53
Mountain Dew
Mountain Dew
70
0
0.3
Diet Mountain Dew
35
70
0.3
Diet Caffeine-Free Mountain Dew
70
0
0.3
Code Red
105
0
53
Diet Code Red
40
72
0
Diet Caffeine-Free
35
70
0.3
Live Wire
65
0
0
Amp
70
9
37
Slice
Cherry Lime
50
0
0
Cherry Spice
35
0
34
Diet Orange
50
90
0
Dr. Slice
35
0
34
Fruit Punch
55
0
0
Grape
70
0
0
Orange-Bold Taste
50
105
0
Peach
65
50
0
Pineapple
70
0
0
Red
55
0
0
Slice Cola
35
0
51
Slice Cola Diet
35
0
41
Strawberry
55
0
0
Mug
Root Beer
65
0
0
Diet Root Beer
70
0
0
Cream Soda
65
0
0
Diet Cream Soda
80
0
0
Fruitworks
Apple Raspberry
110
35
100
Fruit Punch
80
60
123
Guava Berry
80
56
117
Passion Orange
110
60
123
Peach Papaya
110
60
123
Pink Lemonade
80
80
53
Strawberry Melon
110
110
120
Tangerine Citrus
80
35
90
Tropical Berry
80
60
140
Sierra Mist
Sierra Mist
35
48
0
Diet Sierra Mist
35
99
0
Aquafina Essentials
Citrus Blend
50
0
0
Tangerine Pineapple
20
0
49
Watermelon
20
0
0
Wild Berry
40
0
0
Tropicana Fruit Drinks
Fruit Punch
50
90
93
Lemonade
60
40
38
Pink Lemonade
60
39
37
Peach Papaya
50
41
93
Strawberry Melon
50
76
93
Coca-Cola
Coca-Cola Classic
50
0
62
Caffeine-Free Classic
50
0
62
Diet Coke
42
18
27
Caffein-Free Diet Coke
42
18
27
Diet Coke with Lime
42
29
27
Diet Coke with Lemon
42
29
27
Cherry Coke
42
0
56
Diet Cherry Coke
42
18
35
Vanilla Coke
38
0
56
Diet Vanilla Coke
42
29
27
TAB
42
18
45
Citra
60
3
trace
Fresca
36
84
trace
Inca Kola
47
0
0
Diet Inca Kola
51
11
0
Manzana Mia
62
5
trace
Mr. Pibb
Pibb Xtra
42
21
44
Diet Mr. Pibb
39
30
44
Red Flash
32
18
0
Sprite
Sprite
71
0
0
Sprite ReMix
54
0
0
Diet Sprite
36
110
0
Surge
41
53
trace
Barq’s
Root Beer
66
trace
0
Floatz
66
3
0
Diet Root Beer
72
14
0
Red Crème
65
0
0
Diet Red Crème
65
0
0
French Vanilla Crème
66
0
0
Diet French Vanilla Crème
66
trace
0
Fanta
Apple
59
0
0
Berry
33
51
0.2
Grape
45
0
0
Lemon
45
trace
0
Orange
53
0
11
Pineapple
53
0
0
Pink Grapefruit
45
trace
0
Strawberry
45
0
0
Minute Maid
Black Cherry
53
0
0
Blueberry
50
0
0
Fruit Punch
51
20
0
Grape
68
78
0
Grape Medley Fruit Soda
32
63
2
Mixed Berry Fruit Soda
32
59
trace
Peach
50
0
0
Pineapple
47
0
0
Strawberry
50
0
0
Valencia Orange Fruit Soda
33
71
2
Light Valencia Orange Soda
36
89
2
Mello Yello
Mello Yello
50
30
trace
Diet Mello Yello
38
77
trace
Mello Yello Cherry
45
30
trace
Mello Yello Melon
45
30
trace
Coca-Cola Ginger Ale
Northern Neck Ginger Ale
33
23
0
Diet Northern Neck Ginger Ale
36
20
0
Carver’s Ginger Ale
33
23
0
Nestea
Diet Lemon
36
na
0
Honey Lemon Green Tea
35
na
0
Lemon Sweet
35
na
0
Raspberry
38
na
0
Sweetened
38
na
32
Decaffeinated Sweetened
36
na
32
Unsweetened
38
na
32
COOL
COOL
102
na
134
Diet COOL
107
na
159
Lemonade Tea
102
na
68
Peach Frrreezer
102
na
134
Raspberry Cooler
101
na
134
As this table indicates, it is important that renal dietitians stay informed and continue to educate CKD patients on the importance of reading labels. In our efforts to keep dietitians informed, the next Product Update (Part 2) will focus on hidden phosphorus in commonly consumed breakfast foods.
Postscript
More than 10 companies were contacted and asked to provide the nutrition analysis for their beverages. Many were unable to provide such information, and at the time of printing, Campbell’s, the parent company of V-8 Splash and Invigorate, was still processing the request.
Snapple brand was unable to provide a written nutrition analysis of all of their products. However, they were able to assure us that Snapple products are made from 100% natural products without the addition of phosphorus salts.
References
1.
1
Block GS
.
Control of serum phosphorus
(Implication for coronary artery calcification and calcific uremic arteriolopathy (calciphylaxis))
.
Curr Opin Nephrol Hypertens
. 2001;10:741–747
. MEDLINE |
CrossRef
3.
3
Bell RR
, Draper HH
, Tzeng DYM
, et al.
Physiological responses of human adult to foods containing phosphate additives
.
J Nutr
. 1977;107:45–50
.
4.
4
Uribarri J
, Calvo MS
.
Hidden sources of phosphorus in the typical American diet
(Does it matter in nephrology?)
.
Semin Dial
. 2003;16:186–188
. MEDLINE |
CrossRef
DaVita, Inc, Cleve-Hill Dialysis, Buffalo, NY.
Address reprint requests to Lisa Murphy-Gutekunst, MSEd, RD, CSR, DaVita, Inc, Cleve-Hill Dialysis, 1461 Kensington Ave, Buffalo, NY 14215.