Journal of Renal Nutrition
Volume 17, Issue 2 , Pages 126-131 , March 2007

Effects of Omega-3 Fatty Acid Supplementation on Vascular Access Thrombosis in Polytetrafluorethylene Grafts

  • Rodney G. Bowden, PhD

      Affiliations

    • Department of Health, Human Performance, and Recreation, Center for Exercise, Nutrition, and Preventive Health Research, Baylor University
    • Corresponding Author InformationAddress reprint requests to Rodney G. Bowden, PhD, Department of Health, Human Performance, and Recreation, Center for Exercise, Nutrition, and Preventive Health Research, Baylor University, One Bear Place No. 97313, Waco, TX 76798-7313, USA.
    • ,
  • Ronald L. Wilson, MD

      Affiliations

    • Central Texas Nephrology Associates
    • ,
  • Mindy Gentile, MS, RD, LD

      Affiliations

    • Brazos Kidney Center, Waco, Texas.
    • ,
  • Songthip Ounpraseuth, MS

      Affiliations

    • Department of Health, Human Performance, and Recreation, Center for Exercise, Nutrition, and Preventive Health Research, Baylor University
    • ,
  • Page Moore, MS

      Affiliations

    • Department of Health, Human Performance, and Recreation, Center for Exercise, Nutrition, and Preventive Health Research, Baylor University
    • ,
  • Brian C. Leutholtz, PhD

      Affiliations

    • Department of Health, Human Performance, and Recreation, Center for Exercise, Nutrition, and Preventive Health Research, Baylor University

References 

  1. Joseph S, Adler S. Vascular access problems in dialysis patients. Heart Dis. 2001;3:242–247
  2. Shemin D, Lapane KL, Bausserman L, et al. Plasma total homocysteine and hemodialysis access thrombosis: A prospective study. J Am Soc Nephrol. 1999;10:1095–1099
  3. Rodriquez JA, Armadans L, Ferrer E, et al. The function of permanent vascular access. Nephrol Dial Trans. 2000;15:402–408
  4. Feldman HI, Wasserstein A. Hemodialysis vascular access morbidity. J Am Soc Nephrol. 1996;7:523–535
  5. Hojs R, Gorenjak M, Ekart R, et al. Homocysteine and vascular access thrombosis in hemodialysis patients. Renal Failure. 2002;24:215–222
  6. Roy-Chaudhury P, Kelley BS, Narayana A, et al. Hemodialysis vascular access thrombosis dysfunction from basic biology to clinical intervention. Adv Ren Replace Ther. 2002;9:74–78
  7. Feldman HI, Held PJ, Hutchinson JT, et al. Hemodialysis vascular access morbidity in the United States. Kidney Int. 1993;43:1091–1096
  8. Donadio JV. n-3 fatty acids and their role in nephrologic practice. Curr Opin Nephrol Hypertens. 2001;10:639–642
  9. Bowden RG, Wyatt FB, Wilson RL, et al. Homocysteine and vascular access thrombosis in a cohort of end-stage renal disease patients. Ren Fail. 2004;26:709–714
  10. Schmitz PG, McCloud LK, Reikes ST, et al. Prophylaxis of hemodialysis graft thrombosis with fish oil: Double-blind, randomized, prospective trial. J Am Soc Nephrol. 2002;13:184–190
  11. Moist LM, Churchill DN, House AA, et al. Regular monitoring of access flow compared with monitoring of venous pressure fails to improve graft survival. J Am Soc Nephrol. 2003;14:2645–2653
  12. Saran R, Dykstra DM, Wolfe RA, et al. Association between vascular access failure and the use of specific drugs: The Dialysis Outcomes and Practice Patterns Study (DOPPS). Am J Kidney Dis. 2002;40:1255–1263
  13. Sreedhara R, Himmelfarb J, Lazarus JM, et al. Anti-platelet therapy in graft thrombosis: Results of a prospective, randomized double-blind study. Kidney Int. 1994;45:1477–1483
  14. Kaufman JS, O’Conner TZ, Zhang JH, et al. Randomized controlled trial of clopidogrel plus aspirin to prevent hemodialysis access graft thrombosis. J Am Soc Nephrol. 2003;14:2313–2321
  15. Sullivan KL, Besarab A. Hemodynamic screening and early percutaneous intervention reduce hemodialysis access thrombosis and increase graft longevity. J Vasc Interv Radiol. 1997;8:163–170
  16. Schmitz PG, Antony KA. Omega-3 fatty acids in ESRD: Should patients with ESRD eat more fish?. Nephrol Dial Transplant. 2002;17:11–14
  17. Tatsioni A, Chung M, Sun Y, et al. Effects of fish oil supplementation on kidney transplantation: A systematic review and meta-analysis of randomized, controlled trials. J Am Soc Nephrol. 2005;16:2462–2470
  18. Vergili-Nelsen JM. Benefits of fish oil supplementation for hemodialysis patients. J Am Diet Assoc. 2003;103:1174–1177
  19. Bowden RG, Wyatt F, Wilson R. Homocysteine and vascular access thrombosis in end-stage renal disease patients: A retrospective study. J Nephrol. 2002;15:666–670
  20. Diskin CJ, Thomas CE, Zellner CP, et al. Fish oil to prevent intimal hyperplasia and access thrombosis. Nephron. 1990;55:445–447
  21. Freedman LS. Tables of the numbers of patients required in clinical trials using the log-rank test. Stat Med. 1982;1:121–129
  22. Rodriquez JA, Armadans L, Ferrer E, et al. The function of permanent vascular access. Nephrol Dial Trans. 2000;15:402–408
  23. Silver RC, Cain JA. Managing the lifeline: Preemptive access management for better outcomes for hemodialysis patients and programs. Adv Ren Rep Ther. 2000;7(suppl 1):S45–S55

 Data were collected in clinics associated with Central Texas Nephrology Associates.

PII: S1051-2276(06)00163-4

doi: 10.1053/j.jrn.2006.07.009

Journal of Renal Nutrition
Volume 17, Issue 2 , Pages 126-131 , March 2007

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