Journal of Renal Nutrition
Volume 17, Issue 3 , Pages 173-178 , May 2007

Nutritional Effect of Nandrolone Decanoate in Predialysis Patients With Chronic Kidney Disease

  • Somchai Eiam-Ong, MD

      Affiliations

    • Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University Hospital, Bangkok, Thailand
    • Corresponding Author InformationAddress reprint requests to Somchai Eiam-Ong, MD, Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University Hospital, Bangkok, Thailand, 10330.
    • ,
  • Somphon Buranaosot, MD

      Affiliations

    • Nephrology Unit, Internal Medicine, Bangkok Metropolital Administration Hospital, Bangkok, Thailand
    • ,
  • Somchit Eiam-Ong, PhD

      Affiliations

    • Department of Physiology, Faculty of Medicine, Chulalongkorn University Hospital, Bangkok, Thailand.
    • ,
  • Arpar Wathanavaha, MsC

      Affiliations

    • Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University Hospital, Bangkok, Thailand
    • ,
  • Pongsuk Pansin, BsC

References 

  1. National Kidney Foundation. K/DOQI clinical practice guidelines for nutrition in chronic renal failure. Am J Kidney Dis. 2000;35(Suppl 2):S1–S140
  2. Pereira BJG. Optimization of pre-ESRD care: the key to improved dialysis outcomes. Kidney Int. 2000;57:351–365
  3. Bossola M, Muscarifoli M, Tazza L, et al. Malnutrition in hemodialysis patients: what therapy?. Am J Kidney Dis. 2005;46:371–386
  4. Locatelli F, Fouque D, Heimburger O, et al. Nutritional status in dialysis patients: a European consensus. Nephrol Dial Transplant. 2002;17:563–572
  5. Bergstrom J, Lindholm B. Nutrition and adequacy of dialysis (How do hemodialysis and CAPD compare?). Kidney Int Suppl. 1993;43:S39–S50
  6. Aparicio M, Cano N, Chauveau P, et al. Nutritional status of hemodialysis patients: a French National Cooperative Study. Nephrol Dial Transplant. 1999;14:1679–1686
  7. Port F. Morbidity and mortality in dialysis patients. Kidney Int. 1994;46:1728–1737
  8. McCuser FX, Teehan BP, Thorpe KE, et al. Canada-USA (CANUSA) Peritoneal Dialysis Study Group How much peritoneal dialysis is required for the maintenance of a good nutritional state?. Kidney Int. 1996;50(Suppl 56):S56–S61
  9. Lowrie EG, Lew NL. Death risk in hemodialysis patients: the predictive value of commonly measured variables and an evaluation of death rate differences between facilities. Am J Kidney Dis. 1990;15:458–482
  10. Churchill D, Taylor D, Cook R, et al. Canadian hemodialysis morbidity study. Am J Kidney Dis. 1992;19:214–234
  11. Canada-USA Peritoneal Dialysis Study Group. Adequacy of dialysis and nutrition in continuous peritoneal dialysis: association with clinical outcome. J Am Soc Nephrol. 1996;7:198–207
  12. Leavey SF, Strawderman RL, Jones CA, et al. Simple nutritional indicators as independent predictors of mortality in hemodialysis patients. Am J Kidney Dis. 1998;31:997–1006
  13. Combe C, Chauveau P, Laville M. Influence of nutritional factors and hemodialysis adequacy on the survival of 1,610 French patients. Am J Kidney Dis. 2001;37(Suppl 2):S81–S88
  14. Mitch WE. Dietary requirements for protein and calories in the predialysis patient. In:  Mitch WE,  Klahr S editor. Handbook of nutrition and the kidney. fourth edition. Philadelphia: Lippincott Williams and Wilkins; 2002;p. 135–156
  15. Johnson CA. Use of androgens in patients with renal failure. Semin Dial. 2000;13:36–39
  16. Richardson JR, Weinstein MB. Erythropoietic response of dialyzed patients to testosterone administration. Am Intern Med. 1970;73:403–407
  17. DeGown RL, Layender AR, Forland M, et al. Erythropoiesis and erythropoietin in patients with chronic renal failure with hemodialysis and testosterone. Ann Intern Med. 1970;72:913–918
  18. Gaughan WJ, Liss KA, Dunn SR, et al. A 6-month study of low-dose recombinant human erythropoietin alone and in combination with androgens for the treatment of anemia in chronic hemodialysis patients. Am J Kidney Dis. 1997;30:495–500
  19. Teruel JL, Mareen R, Navarro-Antolin J, et al. Androgen versus erythropoietin for the treatment of anemia in hemodialyzed patients a prospective study. J Am Soc Nephrol. 1996;7:140–144
  20. Orr R, Fiatarone Singh M. The anabolic androgenic steroid oxandrolone in the treatment of wasting and catabolic disorders: review of efficacy and safety. Drugs. 2004;64:725–750
  21. Foque D, Guebre-Egziabher F, et al. Advances in anabolic interventions for malnourished dialysis patients. J Ren Nutr. 2003;13:161–165
  22. Gascon A, Belvis JJ, Derisa F, et al. Nandrolone decanoate is a good alternative for the treatment of anemia in elderly male patients on hemodialysis. Geriatr Nephrol Urol. 1999;9:67–72
  23. Johansen KL, Mulligan K, Schambelan M. Anabolic effects of nandrolone decanoate in patients receiving dialysis (A randomized controlled trial). JAMA. 1999;281:1275–1281
  24. Pai B, Chretien C, Lau AH. The effects of nandrolone decanoate on nutritional parameters in hemodialysis patients. Clin Nephrol. 2002;58:38–46
  25. Soliman G, Oreopoulos DG. Anabolic steroids and malnutrition in chronic renal failure. Perit Dial Int. 1994;14:362–365
  26. Dombros NV, Digenis GE, Soliman G, et al. Anabolic steroids in the treatment of malnourished CAPD patients: a retrospective study. Perit Dial Int. 1994;14:344–347
  27. Detsky AS, McLaughlin JR, Baker JP, et al. What is subjective global assessment of nutritional status?. JPEN J Parenter Enteral Nutr. 1987;11:8–13
  28. Kuhn CM. Anabolic steroids. Recent Prog Horm Res. 2002;57:411–434
  29. Bhasin S, Brenner WJ. Emerging issues in androgen replacement therapy. J Clin Endocrinol Metab. 1997;82:3–8
  30. Bagatell CJ, Bremmer WJ. Androgen in men-uses and abuses. Drug Ther. 1996;334:707–714
  31. Bergström J, Lindholm B. Malnutrition, cardiac disease, and mortality: an integrated point of view. Am J Kidney Dis. 1998;32:834–841
  32. Obrador GT, Ruthazer R, Arora P, et al. Prevalence of and factors associated with sub-optimal care prior to initiation of dialysis in the United States. J Am Soc Nephrol. 1999;10:1793–1800
  33. Arora P, Obrador G, Ruthazer R, et al. Prevalence, predictors and consequences of late nephropathy referral at a tertiary care center. J Am Soc Nephrol. 1999;6:1281–1286
  34. Don BR, Kaysen G. Serum albumin: relationship to inflammation and nutrition. Semin Dial. 2004;17:432–437
  35. Watson AJ. Adverse effects of therapy for the correction of anemia in hemodialysis patients. Semin Nephrol. 1989;9(Suppl 1):30–34
  36. Glazer G. Atherogenic effects of anabolic steroids on serum lipid levels (A literature review). Arch Intern Med. 1991;151:1925–1933

PII: S1051-2276(07)00005-2

doi: 10.1053/j.jrn.2007.01.001

Journal of Renal Nutrition
Volume 17, Issue 3 , Pages 173-178 , May 2007

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