Journal of Renal Nutrition
Volume 17, Issue 4 , Pages 282-285, July 2007

A Simplified Approach to Understanding Urea Kinetics in Peritoneal Dialysis

  • Madhukar Misra, MD, FRCP (UK), FASN, FACP

      Affiliations

    • Corresponding Author InformationAddress reprint requests to Madhukar Misra, MD, FRCP (UK), FASN, FACP, Associate Professor of Medicine, Division of Nephrology, University of Missouri Columbia, MA 436, 1 Hospital Drive, Columbia MO 65212.
    • ,
  • Karl Nolph, MD, FRCP

Division of Nephrology, University of Missouri, Columbia, Missouri.

Urea, a small molecular solute, is the candidate molecule commonly used to understand solute kinetics in both peritoneal dialysis (PD) and hemodialysis. Serum urea or serum urea nitrogen levels are used to calculate measures of dialysis adequacy and nutritional status in patients on dialysis. The kinetic behavior of this molecule is different for a continuous therapy such as PD compared with an intermittent therapy such as hemodialysis. This article presents a simplified approach to understanding urea kinetics on PD.

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PII: S1051-2276(07)00042-8

doi:10.1053/j.jrn.2007.02.002

Journal of Renal Nutrition
Volume 17, Issue 4 , Pages 282-285, July 2007

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