Journal of Renal Nutrition
Volume 17, Issue 4 , Pages 282-285 , July 2007

A Simplified Approach to Understanding Urea Kinetics in Peritoneal Dialysis

  • Madhukar Misra, MD, FRCP (UK), FASN, FACP

      Affiliations

    • Corresponding Author InformationAddress reprint requests to Madhukar Misra, MD, FRCP (UK), FASN, FACP, Associate Professor of Medicine, Division of Nephrology, University of Missouri Columbia, MA 436, 1 Hospital Drive, Columbia MO 65212.
  • ,
  • Karl Nolph, MD, FRCP

References 

  1. Levine J, Bernard DB. The role of urea kinetic modeling, TAC urea and Kt/V in achieving optimal dialysis: a critical reappraisal. Am J Kidney Dis. 1990;25:285-229
  2. Lindsay RM, Henderson Lee W. Adequacy of dialysis. Kidney Int. 1998;33(Suppl 24):S92–S99
  3. Held PJ, Port FK, Wolfe RA, et al. The dose of dialysis and patient mortality. Kidney Int. 1996;50:550–556
  4. Borah MD, Schoenfeld PJ, Gotch FA, Sargent JA. Nitrogen balance during intermittent dialysis therapy of uremia. Kidney Int. 1978;31:491–500
  5. Depner TA. Prescribing hemodialysis: a guide to urea modeling. Heidelberg: Kluwer Academic Publishers; 1991;
  6. Mehrotra R, Saran R, Moore HL, et al. Toward targets for initiation of chronic dialysis. Perit Dial Int. 1997;17(5):497–508
  7. Keshaviah P. Urea kinetic and middle molecule approaches to assessing the adequacy of hemodialysis and CAPD. Kidney Int Suppl. 1993;40:S28–S38
  8. Nolph KD. What’s new in peritoneal dialysis-an overview. Kidney Int Suppl. 1992;38:S148–S152
  9. Keshaviah PR, Nolph KD, Van Stone JC. The peak concentration hypothesis.: a urea kinetic approach to comparing the adequacy of continuous ambulatory peritoneal dialysis (CAPD) and hemodialysis. Perit Dial Int. 1989;9:257–260
  10. Clark WR, Henderson LW. Renal vs continuous vs intermittent therapies for removal of uremic toxins. Kidney Int. 2001;59(suppl 78):s298–s303
  11. Henderson L, Leypoldt JK, Lysaght M, Cheung A. Death on dialysis and time/flux tradeoff. Blood Purif. 1997;15:1–14

PII: S1051-2276(07)00042-8

doi: 10.1053/j.jrn.2007.02.002

Journal of Renal Nutrition
Volume 17, Issue 4 , Pages 282-285 , July 2007