Journal of Renal Nutrition
Volume 17, Issue 4 , Pages 250-257 , July 2007

Restricted Protein Diet Is Associated With Decrease in Proteinuria: Consequences on the Progression of Renal Failure

  • Philippe Chauveau, MD

      Affiliations

    • Département de Néphrologie, Hôpital Pellegrin.
    • Corresponding Author InformationAddress reprint requests to Philippe Chauveau, MD, AURAD-Aquitaine, 2 allee des demoiselles, 33170 Gradignan, France.
    • ,
  • Christian Combe, MD

      Affiliations

    • Département de Néphrologie, Hôpital Pellegrin.
    • ,
  • Vincent Rigalleau, MD

      Affiliations

    • Service de Nutrition-Diabétologie, Hôpital Du Haut levêque, Bordeaux, France.
    • ,
  • Benoit Vendrely, MD

      Affiliations

    • Département de Néphrologie, Hôpital Pellegrin.
    • ,
  • Michel Aparicio, MD

      Affiliations

    • Département de Néphrologie, Hôpital Pellegrin.

References 

  1. Ruggenenti P, Perna A, Mosconi L, et al. Urinary protein excretion rate is the best independent predictor of ESRF in non-diabetic proteinuric chronic nephropathies (“Gruppo Italiano di Studi Epidemiologici in Nefrologia” (GISEN)). Kidney Int. 1998;53(5):1209–1216
  2. Remuzzi G, Bertani T. Is glomerulosclerosis a consequence of altered glomerular permeability to macromolecules?. Kidney Int. 1990;38(3):384–394
  3. Bohrer MP, Deen WM, Robertson CR, et al. Mechanism of angiotensin II-induced proteinuria in the rat. Am J Physiol. 1977;233(1):F13–F21
  4. de Zeeuw D, Remuzzi G, Parving HH, et al. Albuminuria, a therapeutic target for cardiovascular protection in type 2 diabetic patients with nephropathy. Circulation. 2004;110(8):921–927
  5. Ruggenenti P, Perna A, Gherardi G, et al. Renoprotective properties of ACE-inhibition in non-diabetic nephropathies with non-nephrotic proteinuria. Lancet. 1999;354(9176):359–364
  6. de Zeeuw D, Remuzzi G, Parving HH, et al. Proteinuria, a target for renoprotection in patients with type 2 diabetic nephropathy: lessons from RENAAL. Kidney Int. 2004;65(6):2309–2320
  7. Kaysen GA, Gambertoglio J, Jimenez I, et al. Effect of dietary protein intake on albumin homeostasis in nephrotic patients. Kidney Int. 1986;29(2):572–577
  8. Aparicio M, Chauveau P, De Precigout V, et al. Nutrition and outcome on renal replacement therapy of patients with chronic renal failure treated by a supplemented very low protein diet. J Am Soc Nephrol. 2000;11(4):708–716
  9. Combe C, Deforges-Lasseur C, Caix J, et al. Compliance and effects of nutritional treatment on progression and metabolic disorders of chronic renal failure. Nephrol Dial Transplant. 1993;8(5):412–418
  10. Ruilope LM, Casal MC, Praga M, et al. Additive antiproteinuric effect of converting enzyme inhibition and a low protein intake. J Am Soc Nephrol. 1992;3(6):1307–1311
  11. Gansevoort RT, de Zeeuw D, de Jong PE. Additive antiproteinuric effect of ACE inhibition and a low-protein diet in human renal disease. Nephrol Dial Transplant. 1995;10(4):497–504
  12. Peterson JC, Adler S, Burkart JM, et al. Blood pressure control, proteinuria, and the progression of renal disease (The Modification of Diet in Renal Disease Study). Ann Intern Med. 1995;123(10):754–762
  13. Walser M, Hill S, Tomalis EA. Treatment of nephrotic adults with a supplemented, very low-protein diet. Am J Kidney Dis. 1996;28(3):354–364
  14. Maroni BJ, Staffeld C, Young VR, et al. Mechanisms permitting nephrotic patients to achieve nitrogen equilibrium with a protein-restricted diet. J Clin Invest. 1997;99(10):2479–2487
  15. Giordano M, De Feo P, Lucidi P, et al. Effects of dietary protein restriction on fibrinogen and albumin metabolism in nephrotic patients. Kidney Int. 2001;60(1):235–242
  16. Ordonez JD, Hiatt RA, Killebrew EJ, et al. The increased risk of coronary heart disease associated with nephrotic syndrome. Kidney Int. 1993;44(3):638–642
  17. Buter H, van Tol A, Navis GJ, et al. Angiotensin II receptor antagonist treatment lowers plasma total and very low + low density lipoprotein cholesterol in type 1 diabetic patients with albuminuria without affecting plasma cholesterol esterification and cholesteryl ester transfer. Diabet Med. 2000;17(7):550–552
  18. Ruggenenti P, Perna A, Remuzzi G. Retarding progression of chronic renal disease: the neglected issue of residual proteinuria. Kidney Int. 2003;63(6):2254–2261
  19. The GISEN Group (Gruppo Italiano di Studi Epidemiologici in Nefrologia). Randomised placebo-controlled trial of effect of ramipril on decline in glomerular filtration rate and risk of terminal renal failure in proteinuric, non-diabetic nephropathy. Lancet. 1997;349(9069):1857–1863
  20. Jafar TH, Stark PC, Schmid CH, et al. Proteinuria as a modifiable risk factor for the progression of non-diabetic renal disease. Kidney Int. 2001;60(3):1131–1140
  21. El Nahas AM, Masters-Thomas A, Brady SA, et al. Selective effect of low protein diets in chronic renal diseases. Br Med J (Clin Res Ed). 1984;289(6455):1337–1341
  22. Apperloo AJ, de Zeeuw D, de Jong PE. Short-term antiproteinuric response to antihypertensive treatment predicts long-term GFR decline in patients with non-diabetic renal disease. Kidney Int Suppl. 1994;45:S174–S178
  23. Rossing P, Hommel E, Smidt UM, et al. Reduction in albuminuria predicts diminished progression in diabetic nephropathy. Kidney Int Suppl. 1994;45:S145–S149

PII: S1051-2276(07)00044-1

doi: 10.1053/j.jrn.2007.02.007

Journal of Renal Nutrition
Volume 17, Issue 4 , Pages 250-257 , July 2007

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