Journal of Renal Nutrition
Volume 19, Issue 2 , Pages 127-135 , March 2009

Association Between Serum Albumin and Mortality in Dialysis Patients Is Partly Explained by Inflammation, and Not by Malnutrition

  • Renée de Mutsert, MSc

      Affiliations

    • Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
    • Corresponding Author InformationAddress reprint requests to Renée de Mutsert, MSc, Department of Clinical Epidemiology, Room C9-19, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands.
    • ,
  • Diana C. Grootendorst, PhD

      Affiliations

    • Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
    • ,
  • Fleur Indemans, BSc

      Affiliations

    • Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
    • ,
  • Elisabeth W. Boeschoten, MD, PhD

      Affiliations

    • Hans Mak Institute, Naarden, The Netherlands
    • ,
  • Raymond T. Krediet, MD, PhD

      Affiliations

    • Department of Nephrology, Academic Medical Center, Amsterdam, The Netherlands
    • ,
  • Friedo W. Dekker, PhD

      Affiliations

    • Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
    • ,
  • for the Netherlands Cooperative Study on the Adequacy of Dialysis-II Study Group

References 

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  3. Leavey SF, Strawderman RL, Jones CA, et al. Simple nutritional indicators as independent predictors of mortality in hemodialysis patients. Am J Kidney Dis. 1998;31:997–1006
  4. Kalantar-Zadeh K, Kilpatrick RD, Kuwae N, et al. Revisiting mortality predictability of serum albumin in the dialysis population: time dependency, longitudinal changes and population-attributable fraction. Nephrol Dial Transplant. 2005;20:1880–1888
  5. Yeun JY, Kaysen GA. Factors influencing serum albumin in dialysis patients. Am J Kidney Dis. 1998;32(Suppl):S118–S125
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  25. Visser R, Dekker FW, Boeschoten EW, et al. Reliability of the 7-point subjective global assessment scale in assessing nutritional status of dialysis patients. Adv Perit Dial. 1999;15:222–225
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  30. Kalantar-Zadeh K, Block G, McAllister CJ, et al. Appetite and inflammation, nutrition, anemia, and clinical outcome in hemodialysis patients. Am J Clin Nutr. 2004;80:299–307
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  32. Kaysen GA, Greene T, Daugirdas JT, et al. Longitudinal and cross-sectional effects of C-reactive protein, equilibrated normalized protein catabolic rate, and serum bicarbonate on creatinine and albumin levels in dialysis patients. Am J Kidney Dis. 2003;42:1200–1211
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 The Netherlands Cooperative Study on the Adequacy of Dialysis-II was supported by unrestricted grants from the Dutch Kidney Foundation and from Amgen BV, Breda, The Netherlands.

 The Netherlands Cooperative Study on the Adequacy of Dialysis-II Study Group includes A.J. Apperloo, J.A. Bijlsma, M. Boekhout, W.H. Boer, P.J.M. van der Boog, H.R. Büller, M. van Buren, F.T. de Charro, C.J. Doorenbos, M.A. van den Dorpel, A. van Es, W.J. Fagel, G.W. Feith, C.W.H. de Fijter, L.A.M. Frenken, J.A.C.A. van Geelen, P.G.G. Gerlag, J.P.M.C. Gorgels, W. Grave, R.M. Huisman, K.J. Jager, K. Jie, W.A.H. Koning-Mulder, M.I. Koolen, T.K. Kremer Hovinga, A.T.J. Lavrijssen, A.J. Luik, J. van der Meulen, K.J. Parlevliet, M.H.M. Raasveld, F.M. van der Sande, M.J.M. Schonck, M.M.J. Schuurmans, C.E.H. Siegert, C.A. Stegeman, P. Stevens, J.G.P. Thijssen, R.M. Valentijn, G.H. Vastenburg, C.A. Verburgh, H.H. Vincent, and P.F. Vos.

PII: S1051-2276(08)00389-0

doi: 10.1053/j.jrn.2008.08.003

Journal of Renal Nutrition
Volume 19, Issue 2 , Pages 127-135 , March 2009

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