Journal of Renal Nutrition
Volume 19, Issue 2 , Pages 145-152 , March 2009

Effects of Peridialytic Oral Supplements on Nutritional Status and Quality of Life in Chronic Hemodialysis Patients

  • Meri Kay Scott, PhD

      Affiliations

    • Clinical Development Organization, Eli Lilly and Co., Indianapolis, Indiana
    • ,
  • Niyati A. Shah, MS

      Affiliations

    • MBA Candidate, Columbia Business School, Columbia University, New York, New York
    • ,
  • A. Mary Vilay, PharmD

      Affiliations

    • Department of Clinical, Social, and Administrative Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan
    • ,
  • Joseph Thomas III, PhD

      Affiliations

    • Department of Pharmacy Practice, School of Pharmacy and Pharmaceutical Sciences, Purdue University, West Lafayette, Indiana
    • ,
  • Michael A. Kraus, MD

      Affiliations

    • Division of Nephrology, Department of Medicine, School of Medicine, Indiana University, Indianapolis, Indiana
    • ,
  • Bruce A. Mueller, PharmD, FCCP

      Affiliations

    • Department of Clinical, Social, and Administrative Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan
    • Corresponding Author InformationAddress reprint requests to Bruce A. Mueller, PharmD, FCCP, Department of Clinical, Social, and Administrative Sciences, College of Pharmacy, University of Michigan, 428 Church St., Ann Arbor, MI 48109-1065.

References 

  1. Marcen R, Teruel JL, de la Cal MA, et al. The impact of malnutrition in morbidity and mortality in stable haemodialysis patients. Nephrol Dial Transplant. 1997;12:2324–2331
  2. Leavey SF, Strawderman RL, Jones CA, et al. Simple nutritional indicators as independent predictors of mortality in hemodialysis patients. Am J Kidney Dis. 1998;31:997–1006
  3. Qureshi AR, Alvestrand A, Danielsson A, et al. Factors predicting malnutrition in hemodialysis patients: a cross sectional study. Kidney Int. 1998;53:773–782
  4. Laws RA, Tapsell LC, Kelly J. Nutritional status and its relationship to quality of life in a sample of chronic hemodialysis patients. J Ren Nutr. 2000;10:139–147
  5. Rocco MV, Paranandi L, Burrowes JD, et al. Nutritional status in the HEMO Study cohort at baseline. Am J Kidney Dis. 2002;39:245–256
  6. Ikizler TA, Wingard RL, Harvell J, et al. Association of morbidity with markers of nutrition and inflammation in chronic hemodialysis patients: a prospective study. Kidney Int. 1999;55:1945–1951
  7. Herselman M, Moosa MR, Kotze TJ, et al. Protein-energy malnutrition is a risk factor for increased morbidity in long-term hemodialysis patients. J Ren Nutr. 2000;10:7–15
  8. Lowrie EG, Lew NL. Death risk in hemodialysis patients: the predictive value of commonly measured variables and an evaluation of death rate differences between facilities. Am J Kidney Dis. 1990;15:458–482
  9. Owen WF, Lew NL, Liu Y, et al. The urea reduction ratio and serum albumin concentration as predictors of mortality in patients undergoing hemodialysis. N Engl J Med. 1993;329:1001–1006
  10. Pifer TB, McCullough KP, Port FK, et al. Mortality risk in hemodialysis patients and changes in nutritional indicators: DOPPS. Kidney Int. 2002;62:2238–2245
  11. Dwyer JT, Larive B, Leung J, et al. Are nutritional status indicators associated with mortality in the Hemodialysis (HEMO) Study?. Kidney Int. 2005;68:1766–1776
  12. Ohri-Vachaspati P, Sehgal AR. Quality of life implications of inadequate protein nutrition among hemodialysis patients. J Ren Nutr. 1999;9:9–13
  13. Allen KL, Miskulin D, Yan G, et al. Association of nutritional markers with physical and mental health status in prevalent hemodialysis patients from the HEMO Study. J Ren Nutr. 2002;12:160–169
  14. Raimundo P, Ravasco P, Proenca V, et al. Does nutrition play a role in the quality of life of patients under chronic haemodialysis?. Nutr Hosp. 2006;21:139–144
  15. Foulks CJ. An evidence-based evaluation of intradialytic parenteral nutrition. Am J Kidney Dis. 1999;33:186–192
  16. Cano NJM, Fouque D, Roth H, et al. Intradialytic parenteral nutrition does not improve survival in malnourished hemodialysis patients: a 2-year multicenter, prospective, randomized study. J Am Soc Nephrol. 2007;18:2583–2591
  17. Bruce D, Laurance I, McGuiness M, et al. Nutritional supplements after hip fracture: poor compliance limits effectiveness. Clin Nutr. 2003;22:497–500
  18. Roberts M, Potter J, McColl J, et al. Can prescription of sip-feed supplements increase energy intake in hospitalized older adults with medical problems?. Br J Nutr. 2003;90:425–429
  19. Lad H, Gott M, Gariballa S. Elderly patients’ compliance and elderly patients’ and health professionals’ views, and attitudes towards prescribed sip-feed supplements. J Nutr Health Aging. 2005;9:310–314
  20. Miller MD, Daniels LA, Bannerman E, et al. Adherence to nutrition supplements among patients with a fall-related lower limb fracture. Nutr Clin Pract. 2005;20:569–578
  21. Hays RD, Kallich JD, Mapes ML, et al. Kidney disease quality of life short form (KDQOL-SF™), version 1.3: a manual for use and scoring. Santa Monica, CA: Rand Corp.; 1997;
  22. Charlson ME, Pompei P, Ales KL, et al. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40:373–383
  23. Berneis K, Iseli-Schaub J, Garbani E, et al. Effects of intradialytic parenteral nutrition in chronic haemodialysis patients with malnutrition: a pilot study. Wien Klin Wochenschr. 1999;111:876–881
  24. Mortelmans AK, Duym P, Vandenbroucke J, et al. Intradialytic parenteral nutrition in malnourished hemodialysis patients: a prospective long-term study. J Parenter Enteral Nutr. 1999;23:90–95
  25. Cherry N, Shalansky K. Efficacy of intradialytic parenteral nutrition in malnourished hemodialysis patients. Am J Health System Pharm. 2002;59:1736–1741
  26. Stratton RJ, Bircher G, Fouque D, et al. Multinutrient oral supplements and tube feeding in maintenance dialysis: a systematic review and meta-analysis. Am J Kidney Dis. 2005;46:387–405
  27. Caglar K, Fedje L, Dimmitt R, et al. Therapeutic effects of oral nutritional supplementation during hemodialysis. Kidney Int. 2002;62:1054–1059
  28. Sharma M, Rao M, Jacob S, et al. A controlled trial of intermittent enteral nutrient supplementation in maintenance hemodialysis patients. J Ren Nutr. 2002;12:229–237
  29. Kaysen GA, Stevenson FT, Depner TA. Determinants of albumin concentration in hemodialysis patients. Am J Kidney Dis. 1997;29:658–668
  30. Bologa RM, Levine DM, Parker TS, et al. Interleukin-6 predicts hypoalbuminemia, hypocholesterolemia, and mortality in hemodialysis patients. Am J Kidney Dis. 1998;32:107–114
  31. Locatelli F, Andrulli S, Memoli B, et al. Nutritional-inflammation status and resistance to erythropoietin therapy in haemodialysis patients. Nephrol Dial Transplant. 2006;21:991–998
  32. Agarwal R, Davis JL, Smith L. Serum albumin is strongly associated with erythropoietin sensitivity in hemodialysis patients. Clin J Am Soc Nephrol. 2008;3:98–104
  33. Hays RD, Kallich JD, Mapes DL, et al. Development of the kidney disease quality of life (KDQOL™) instrument. Qual Life Res. 1994;3:329–338
  34. Sehgal AR, Leon J, Soinski JA. Barriers to adequate protein nutrition among hemodialysis patients. J Ren Nutr. 1998;8:179–187
  35. Wilson G, Molaison EF, Pope J, et al. Nutritional status and food insecurity in hemodialysis patients. J Ren Nutr. 2006;16:54–58

 This work was conducted at the Outpatient Hemodialysis Center, Indiana University Hospital, Indianapolis, Indiana.

 This study was presented at the American Society of Nephrology Annual Meeting, November 1999, Miami, Florida.

PII: S1051-2276(08)00390-7

doi: 10.1053/j.jrn.2008.08.004

Journal of Renal Nutrition
Volume 19, Issue 2 , Pages 145-152 , March 2009

Article Tools

* Image Usage & Resolution