Journal of Renal Nutrition
Volume 19, Issue 2 , Pages 178-182 , March 2009

Influence of Renal Function and Diet on Acid-Base Status in Chronic Kidney Disease Patients

  • Viviane O. Leal, MS

      Affiliations

    • Division of Neprology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
    • ,
  • Alvimar G. Delgado, MD, PhD

      Affiliations

    • Division of Neprology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
    • ,
  • Maurilo Leite Jr., MD, PhD

      Affiliations

    • Division of Neprology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
    • ,
  • William E. Mitch, MD

      Affiliations

    • Division of Nephrology, Baylor College of Medicine, Houston, Texas
    • ,
  • Denise Mafra, PhD

      Affiliations

    • Department of Clinical Nutrition, Federal Fluminense University, Niterói, Brazil
    • Corresponding Author InformationAddress reprint requests to Denise Mafra, PhD, 27 Avenue Lacassagne, Lyon 69003, France.

References 

  1. Mitch WE. Malnutrition: a frequent misdiagnosis for hemodialysis patients. J Clin Invest. 2002;110:437–439
  2. Kovacic V, Roguljic L, Kovacic V. Metabolic acidosis of chronically haemodialysed patients. Am J Nephrol. 2003;23:158–164
  3. Mehrotra R, Kopple JD, Wolfson M. Metabolic acidosis in maintenance dialysis patients: clinical considerations. Kidney Int. 2003;88(Suppl.):S13–S25
  4. Du Z, Hu D, Mitch WE. Molecular mechanisms activating muscle protein degradation in chronic kidney disease and other catabolic conditions. Eur J Clin Invest. 2005;35:157–163
  5. Nuhad I. Use of erythropoietin, active vitamin D3 metabolites and alkali agents in predialysis patients. Semin Nephrol. 1997;17:270–284
  6. Frassetto LA, Todd KM, Morris CJ, et al. Estimation of net endogenous noncarbonic acid production in humans from diet potassium and protein contents. Am J Clin Nutr. 1998;68:576–583
  7. Caravaca F, Arrobas M, Pizarro JL, et al. Metabolic acidosis in advanced renal failure: differences between diabetic and nondiabetic patients. Am J Kidney Dis. 1999;33:892–898
  8. Messa P, Mioni G, Di Maio G, et al. Derangement of acid-base balance in uremia and under hemodialysis. J Nephrol. 2001;14(Suppl. 4):14–21
  9. Wiseman AC, Linas S. Disorders of potassium and acid-base balance. Am J Kidney Dis. 2005;45:941–949
  10. Bommer J, Locatelli F, Satayathum S, et al. Association of predialysis serum bicarbonate levels with risk of mortality and hospitalization in the Dialysis Outcomes and Practice Patterns Study (DOPPS). Am J Kidney Dis. 2004;44:661–667
  11. Soudan K, Ricanati ES, Leon JB, et al. Determinants of metabolic acidosis among hemodialysis patients. Hemodial Int. 2006;10:209–214
  12. Remer T. Influence of diet on acid-base balance. Semin Dial. 2000;13:221–226
  13. Remer T. Influence of nutrition on acid-base balance. Eur J Nutr. 2001;40:214–220
  14. Remer T, Manz F. Potential renal acid loads of foods and its influence on urine pH. J Am Diet Assoc. 1995;95:791–797
  15. Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron. 1979;16:31–41
  16. World Health Organization: Physical status: the use and interpretation of anthropometry. Report of a WHO expert committee (WHO technical report series, no. 854). Geneva: World Health Organization; 1995;
  17. Frisancho AR. New norms of upper limb fat and muscle areas for assessment of nutritional status. Am J Clin Nutr. 1981;34:2540–2545
  18. Du J, Wang X, Meireles CL, et al. Activation of caspase 3 is an initial step triggering muscle proteolysis in catabolic conditions. J Clin Invest. 2004;113:115–123
  19. Bailey JL, Zheng B, Hu Z, et al. Chronic kidney disease causes defects in signaling through the insulin receptor substrate/phosphatidylinositol 3-kinase/Akt pathway: implications for muscle atrophy. J Am Soc Nephrol. 2006;17:1388–1394
  20. Lee SW, Dai G, Hu Z, et al. Regulation of muscle protein degradation: coordinated control of apoptotic and ubiquitin-proteasome systems by phosphatidylinositol 3 kinase. J Am Soc Nephrol. 2004;15:1537–1545
  21. Workeneh BT, Rondon-Berrios H, Zhang L, et al. Development of a diagnostic method for detecting increased muscle protein degradation in patients with catabolic conditions. J Am Soc Nephrol. 2006;17:3233–3239
  22. Pickering WP, Price SR, Bircher G, et al. Nutrition in CAPD: serum bicarbonate and the ubiquitin-proteasome system in muscle. Kidney Int. 2002;61:1286–1292
  23. Chaveau P, Fouque D, Combe C, et al. Acidosis and status nutritional in haemodialysed patients. French Study Group for Nutrition in Dialysis. Semin Dial. 2000;13:241–246
  24. Wang XH, Hu Z, Hu JP, et al. Insulin resistance accelerates muscle protein degradation: activation of the ubiquitin-proteasome pathway by defects in muscle cell signaling. Endocrinology. 2006;147:4160–4168
  25. Raj DSC, Shah H, Shah VO, et al. Markers of inflammation, proteolysis, and apoptosis in ESRD. Am J Kidney Dis. 2003;42:1212–1220
  26. Zocalli C, Mallamaci F, Tripepi G. Adipose tissue as a source of inflammatory cytokines in healthy and disease: focus on end-stage renal disease. Kidney Int. 2005;63(Suppl. 84):65–68
  27. Hara Y, May RC, Kelly RA, et al. Acidosis, not azotemia, stimulates branched-chain amino acid catabolism in uremic rats. Kidney Int. 1987;32:808–814
  28. Mitch WE, Remuzzi G. Diets for patients with chronic kidney disease: still worth prescribing. J Am Soc Nephrol. 2004;15:234–237
  29. National Kidney Foundation: K/DOQI. Clinical practice guidelines for chronic kidney disease: evaluation, classification and stratification. Kidney Disease Outcome Quality Initiative. Part 4. Definition and classification of stages of chronic kidney disease. Am J Kidney Dis. 2002;39(Suppl.):S46–S75
  30. Cupisti A, D'Alessandro C, Morelli E, et al. Nutritional status and dietary manipulation in predialysis chronic renal failure patients. J Ren Nutr. 2004;14:127–133
  31. Fouque D, Laville M, Boissel JP. Low protein diets for chronic renal failure in non-diabetic adults (Cochrane review). Cochrane Database Syst Rev. 2006;2:CD001892
  32. Hsu CY, Chertow GM. Elevations of serum phosphorus and potassium in mild to moderate chronic renal insufficiency. Nephrol Dial Transplant. 2002;17:1419–1425

 This study was supported by Programa Institucional de Bolsas de Iniciação Científica-Conselho Nacional de Desenvolvimento Científicoe Tecnológico and Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.

PII: S1051-2276(08)00396-8

doi: 10.1053/j.jrn.2008.08.010

Journal of Renal Nutrition
Volume 19, Issue 2 , Pages 178-182 , March 2009

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