Journal of Renal Nutrition
Volume 19, Issue 3 , Pages 220-227 , May 2009

Association Between C-Reactive Protein and Biomarkers of Bone and Mineral Metabolism in Chronic Hemodialysis Patients: A Cross-Sectional Study

  • Chien-Te Lee, MD, PhD

      Affiliations

    • Division of Nephrology, Department of Medicine, Chang-Gung Memorial Hospital-Kaohsiung Medical Center, Chang-Gung University College of Medicine, Niao-Sung Shang, Kaohsiung, Hsien, Taiwan
    • Corresponding Author InformationAddress reprint requests to Chien-Te Lee, MD, PhD, Division of Nephrology, Department of Internal Medicine, Chang-Gung Memorial Hospital, 123 Ta-Pei Road, Niao-Sung Shang, Kaohsiung, Hsien 833, Taiwan.
    • ,
  • Yu-Che Tsai, MD

      Affiliations

    • Division of Nephrology, Department of Medicine, Chang-Gung Memorial Hospital-Kaohsiung Medical Center, Chang-Gung University College of Medicine, Niao-Sung Shang, Kaohsiung, Hsien, Taiwan
    • ,
  • Hwee-Yeong Ng, MD

      Affiliations

    • Division of Nephrology, Department of Medicine, Chang-Gung Memorial Hospital-Kaohsiung Medical Center, Chang-Gung University College of Medicine, Niao-Sung Shang, Kaohsiung, Hsien, Taiwan
    • ,
  • Yih Su, PhD

      Affiliations

    • Department of International Trade, Cheng Shiu University, Kaohsiung, Taiwan
    • ,
  • Wen-Chin Lee, MD, PhD

      Affiliations

    • Division of Nephrology, Department of Medicine, Chang-Gung Memorial Hospital-Kaohsiung Medical Center, Chang-Gung University College of Medicine, Niao-Sung Shang, Kaohsiung, Hsien, Taiwan
    • ,
  • Lung-Chih Lee, MD

      Affiliations

    • Division of Nephrology, Department of Medicine, Chang-Gung Memorial Hospital-Kaohsiung Medical Center, Chang-Gung University College of Medicine, Niao-Sung Shang, Kaohsiung, Hsien, Taiwan
    • ,
  • Terry Ting-Yu Chiou, MD

      Affiliations

    • Division of Nephrology, Department of Medicine, Chang-Gung Memorial Hospital-Kaohsiung Medical Center, Chang-Gung University College of Medicine, Niao-Sung Shang, Kaohsiung, Hsien, Taiwan
    • ,
  • Shang-Chih Liao, MD

      Affiliations

    • Division of Nephrology, Department of Medicine, Chang-Gung Memorial Hospital-Kaohsiung Medical Center, Chang-Gung University College of Medicine, Niao-Sung Shang, Kaohsiung, Hsien, Taiwan
    • ,
  • Kao-Tai Hsu, MD

      Affiliations

    • Division of Nephrology, Department of Medicine, Chang-Gung Memorial Hospital-Kaohsiung Medical Center, Chang-Gung University College of Medicine, Niao-Sung Shang, Kaohsiung, Hsien, Taiwan

References 

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  15. Tomasello S, Dhupar S, Sherman R. Phosphate binders, K/DOQI guidelines, and compliance: the unfortunate reality. Dial Transplant. 2004;33:236–242
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  17. Kalantar-Zadeh K, Kuwae N, Regidor DL, et al. Survival predictability of time-varying indicators of bone disease in maintenance hemodialysis patients. Kidney Int. 2006;70:771–780
  18. Blacher J, Guerin AP, Pannier B, et al. Arterial calcifications, arterial stiffness, and cardiovascular risk in end-stage renal disease. Hypertension. 2001;38:938–942
  19. Wang AY, Wang M, Woo J, et al. Cardiac valve calcification as an important predictor for all-cause mortality and cardiovascular mortality in long-term peritoneal dialysis patients: a prospective study. J Am Soc Nephrol. 2003;14:159–168
  20. London GM, Marchais SJ, Guerin AP, et al. Arteriosclerosis, vascular calcifications and cardiovascular disease in uremia. Curr Opin Nephrol Hypertens. 2005;14:525–531
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  23. Floege J, Ketteler M. Vascular calcification in patients with end-stage renal disease. Nephrol Dial Transplant. 2004;19(Suppl 5):v59–v66
  24. Ketteler M. Fetuin-A and extraosseous calcification in uremia. Curr Opin Nephrol Hypertens. 2005;14:337–342
  25. Brancaccio D, Tetta C, Gallieni M, et al. Inflammation, CRP, calcium overload and a high calcium-phosphate product: a “liaison dangereuse. Nephrol Dial Transplant. 2002;17:201–203
  26. Block GA, Hulbert-Shearon TE, Levin NW, et al. Association of serum phosphorus and calcium × phosphate product with mortality risk in chronic hemodialysis patients: a national study. Am J Kidney Dis. 1998;31:607–617
  27. Movilli E, Feliciani A, Camerini C, et al. A high calcium-phosphate product is associated with high C-reactive protein concentrations in hemodialysis patients. Nephron Clin Pract. 2005;101:c161–c167
  28. Kalpakian MA, Mehrotra R. Vascular calcification and disordered mineral metabolism in dialysis patients. Semin Dial. 2007;20:139–143

PII: S1051-2276(08)00461-5

doi: 10.1053/j.jrn.2008.11.004

Journal of Renal Nutrition
Volume 19, Issue 3 , Pages 220-227 , May 2009

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