Journal of Renal Nutrition
Volume 19, Issue 5 , Pages 389-395 , September 2009

Effects of Soy Consumption on Oxidative Stress, Blood Homocysteine, Coagulation Factors, and Phosphorus in Peritoneal Dialysis Patients

  • H. Imani, MSc

      Affiliations

    • Department of Human Nutrition, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shaheed Beheshti University of Medical Sciences and Health Services, Tehran, Islamic Republic of Iran
    • ,
  • H. Tabibi, PhD

      Affiliations

    • Department of Human Nutrition, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shaheed Beheshti University of Medical Sciences and Health Services, Tehran, Islamic Republic of Iran
    • Corresponding Author InformationAddress reprint requests to Hadi Tabibi, Department of Human Nutrition, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, 46 West Arghavan St., Farahzadi Blvd., Shahrak Qods, PO, Box 19395-4741 Tehran, Islamic Republic of Iran.
    • ,
  • S. Atabak, MD

      Affiliations

    • Department of Nephrology, Shaheed Modares Hospital, Shaheed Beheshti University of Medical Sciences and Health Services, Tehran, Islamic Republic of Iran
    • ,
  • L. Rahmani, MSc

      Affiliations

    • Department of Nursing, Shaheed Modares Hospital, Tehran, Islamic Republic of Iran
    • ,
  • M. Ahmadinejad, MD

      Affiliations

    • Iranian Blood Transfusion Organization, Tehran, Islamic Republic of Iran
    • ,
  • M. Hedayati, PhD

      Affiliations

    • Endocrine Research Center, Shaheed Beheshti University of Medical Sciences and Health Services, Tehran, Islamic Republic of Iran

References 

  1. Singh AK, Brenner BM. Dialysis in the treatment of renal failure. In:  Kasper DL,  Braunwald E,  Fauci AS, et al. editor. Harrison's principles of internal medicine. 16th ed. New York: McGraw-Hill; 2005;p. 1663–1667
  2. Jungers P, Nguyen Khoa T, Massy ZA, et al. Incidence of atherosclerotic arterial occlusive accidents in predialysis and dialysis patients: a multicentric study in the Ile de France district. Nephrol Dial Transplant. 1999;14:898–902
  3. Malgorzewicz S, Lichodziejewska-Niemierko M, Rutkowski B, et al. Nutritional status and oxidative processes in diabetic and nondiabetic peritoneal dialysis patients. J Ren Nutr. 2004;14:242–247
  4. Perna AF, De Santo NG. Homocysteine. In:  Kopple JD,  Massary SG editor. Kopple and Massary's nutritional management of renal disease. 2nd ed. Philadelphia: Lippincott Williams & Wilkins; 2004;p. 117–123
  5. Kobayashi M, Yorioka N, Yamakido M. Hypercoagulability and secondary hyperfibrinolysis may be related to abnormal lipid metabolism in patients treated with continuous ambulatory peritoneal dialysis. Nephron. 1997;76:56–61
  6. Tomura S, Nakamura Y, Doi M, et al. Fibrinogen, coagulation factor VII, tissue plasminogen activator, plasminogen activator inhibitor-1, and lipid as cardiovascular risk factors in chronic hemodialysis and continuous ambulatory peritoneal dialysis patients. Am J Kidney Dis. 1996;27:848–854
  7. Jenkins DJ, Kendall CW, Jackson CJ, et al. Effects of high- and low-isoflavone soy foods on blood lipids, oxidized LDL, homocysteine, and blood pressure in hyperlipidemic men and women. Am J Clin Nutr. 2002;76:365–372
  8. Nagata C, Shimizu H, Takami R, et al. Soy product intake is inversely associated with serum homocysteine level in premenopausal Japanese women. J Nutr. 2003;133:797–800
  9. Tonstad S, Smerud K, Høie L. A comparison of the effects of 2 doses of soy protein or casein on serum lipids, serum lipoproteins, and plasma total homocysteine in hypercholesterolemic subjects. Am J Clin Nutr. 2002;76:78–84
  10. Dent SB, Peterson CT, Brace LD, et al. Soy protein intake by perimenopausal women does not affect circulating lipids and lipoproteins or coagulation and fibrinolytic factors. J Nutr. 2001;131:2280–2287
  11. Wilcox JN, Blumenthal BF. Thrombotic mechanisms in atherosclerosis: potential impact of soy proteins. J Nutr. 1995;125(Suppl):631S–638S
  12. Engelman HM, Alekel DL, Hanson LN, et al. Blood lipid and oxidative stress responses to soy protein with isoflavones and phytic acid in postmenopausal women. Am J Clin Nutr. 2005;81:590–596
  13. Steinberg FM, Guthrie NL, Villablanca AC, et al. Soy protein with isoflavones has favorable effects on endothelial function that are independent of lipid and antioxidant effects in healthy postmenopausal women. Am J Clin Nutr. 2003;78:123–130
  14. Jenkins DJ, Kendall CW, Garsetti M, et al. Effect of soy protein foods on low-density lipoprotein oxidation and ex vivo sex hormone receptor activity—a controlled crossover trial. Metabolism. 2000;49:537–543
  15. Carlson TH. Laboratory data in nutrition assessment. In:  Mahan LK,  Escott-Stump S editor. Krause's food, nutrition, and diet therapy. 11th ed. Philadelphia: W.B. Saunders; 2004;p. 450
  16. Perna AF. Homocysteine. In:  Massry SG,  Glassock RJ editor. Massry and Glassock's textbook of nephrology. 4th ed. Philadelphia: Williams & Wilkins; 2001;p. 1258–1261
  17. Williams SR. Nutrition and diet therapy. 8th ed. Baltimore: Mosby; 1997;pp 746-747
  18. Reimann M, Dierkes J, Carlsohn A, et al. Consumption of soy isoflavones does not affect plasma total homocysteine or asymmetric dimethylarginine concentrations in healthy postmenopausal women. J Nutr. 2006;136:100–105
  19. Hanson LN, Engelman HM, Alekel DL, et al. Effects of soy isoflavones and phytate on homocysteine, C-reactive protein, and iron status in postmenopausal women. Am J Clin Nutr. 2006;84:774–780
  20. Shorecki K, Green J, Brenner BM. Chronic renal failure. In:  Kasper DL,  Braunwald E,  Fauci AS, et al. editor. Harrison's principles of internal medicine. 16th ed. New York: McGraw-Hill; 2005;p. 1653–1663
  21. Chicago Dietetic Association, South Suburban Dietetic Association, Dietitians of Canada: Manual of clinical dietetics. 6th ed.. Chicago: American Dietetic Association; 2000;pp 455-456
  22. Sutton D, Higgins B, Stevens JM. Continuous ambulatory peritoneal dialysis patients are unable to increase dietary intake to recommended levels. J Ren Nutr. 2007;17:329–335
  23. Dong J, Fan M, Qi H, Gan H, Liu H, Wang H. Clinical study on malnutrition and low take of protein and energy in peritoneal dialysis patients. Zhonghua Yi Xue Za Zhi. 2002;82:61–65
  24. Prasad N, Gupta A, Sinha A, Sharma RK, Kumar A, Kumar R. Changes in nutritional status on follow-up of an incident cohort of continuous ambulatory peritoneal dialysis patients. J Ren Nutr. 2008;18:195–201
  25. Kopple JD. McCollum Award Lecture, 1996: Protein-energy malnutrition in maintenance dialysis patients. Am J Clin Nutr. 1997;65:1544–1557

 This study was supported by the National Nutrition and Food Technology Research Institute of Iran.

PII: S1051-2276(09)00042-9

doi: 10.1053/j.jrn.2009.01.020

Journal of Renal Nutrition
Volume 19, Issue 5 , Pages 389-395 , September 2009

Article Tools