Journal of Renal Nutrition
Volume 20, Issue 1 , Pages 44-51 , January 2010

Assessment of Prealbumin in Hemodialysis and Renal-Transplant Patients

  • Stavroula Chrysostomou, SRD, MSc

      Affiliations

    • Medical School of Athens, National and Kapodistrian University of Athens, Athens, Greece
    • Corresponding Author InformationAddress reprint requests to Stavroula Chrysostomou, SRD, MSc, P.O. Box 30591, Ayia Napa-Famagusta, 5344 Cyprus, Greece.
    • ,
  • Chalalambos Stathakis, MD, PhD

      Affiliations

    • Division of Nephrology, Laikon General Hospital of Athens, Athens, Greece
    • ,
  • George Petrikkos, MD, PhD

      Affiliations

    • Medical School of Athens, National and Kapodistrian University of Athens, Athens, Greece
    • ,
  • George Daikos, MD, PhD

      Affiliations

    • Medical School of Athens, National and Kapodistrian University of Athens, Athens, Greece
    • ,
  • Athina Gompou, MD

      Affiliations

    • Division of Nephrology, Laikon General Hospital of Athens, Athens, Greece
    • ,
  • Despina Perrea, PhD

      Affiliations

    • Medical School of Athens, National and Kapodistrian University of Athens, Athens, Greece
    • Christeas Hall Laboratory for Experimental Surgery and Surgical Research, University of Athens, Athens, Greece

References 

  1. Chertow GM, Ackert K, Lew NL, et al. Prealbumin is as important as albumin in the nutritional assessment of hemodialysis patients. Kidney Int. 2000;58:2512–2517
  2. Avram MM, Blaustein D, Fein PA, et al. Hemoglobin predicts long-term survival in dialysis patients: A 15-year single-center longitudinal study and a correlation trend between prelbumin and haemoglobin. Kidney Int. 2003;64(Suppl):S6–S11
  3. Alangaden GJ, Thyagarajan R, Gruber SA, et al. Infectious complications after kidney transplantation: current epidemiology and associated risk factors. Clin Transplant. 2006;20:401–409
  4. Kamar N, Mariat Ch, Delahousse M, et al. Diabetes mellitus after kidney transplantation: a French multicentre observational study. Nephrol Dial Transplant. 2007;22:1986–1993
  5. Monier-Faugere M, Mawad H, Qi Q, et al. High prevalence of low bone turnover and occurrence of osteomalacia after kidney transplantation. J Am Soc Nephrol. 2000;11:1093–1099
  6. Pischon T, Sharma A: Obesity as a risk factor in renal transplant patients. Nephrol Dial Transplant 16:14–17
  7. Kasiske BL, Vazquez MA, Harmon WE, et al. Recommendations for the outpatient surveillance of renal transplant recipients. J Am Soc Nephrol. 2000;11(Suppl):S1–S86
  8. Potter MA, Luxton G. Prealbumin measurement as a screening tool for protein calorie malnutrition in emergency hospital admissions: a pilot study. Clin Invest Med. 1999;22:44–52
  9. Bernsteln LH, Loukhardt-Falrfield CJ, Pleben W, et al. Usefulness of data on albumin and prealbumin concentrations in determining effectiveness of nutritional support. Clin Chem. 1989;35:271–274
  10. National Kidney Foundation. K/DOQI clinical practical guidelines for chronic kidney disease: evaluation, classification and stratification. Am J Kidney Dis. 2002;39(Suppl):S1–S266
  11. World Health Organization. WHO consultation on obesity. Preventing and managing the global epidemic. Geneva: World Health Organization; 1997;
  12. Spiekerman AM. Proteins used in nutritional assessment. Clin Lab Med. 1993;13:353–369
  13. Fellah H, Omar S, Feki M, et al. Is serum transthyretin a reliable marker of nutritional status in patients with end-stage renal disease?. Clin Biochem. 2008;41:493–497
  14. Don BR, Kaysen G. Serum albumin: relationship to inflammation and nutrition. Semin Dial. 2004;17:432–437
  15. Chertow GM, Goldstein-Fuchs DJ, Lazarus JM, et al. Prealbumin, mortality, and cause-specific hospitalization in hemodialysis patients. Kidney Int. 2005;68:2794–2800
  16. Aakhus S, Dahl K, Wideroe TE. Cardiovascular morbidity and risk factors in renal transplant patients. Nephrol Dial Transplant. 1999;14:648–654
  17. Locatelli F, Fouque D, Heimburger O, et al. Nutritional status in dialysis patients: A European consensus. Nephrol Dial Transplant. 2002;17:563–572
  18. Marcen R. Cardiovascular risk factors in renal transplantation-current controversies. Nephrol Dial Transplant. 2006;21(Suppl 3):iii3-iii8
  19. First MR. Renal function as a predictor of long-term graft survival in renal transplant patients. Nephrol Dial Transplant. 2003;18(Suppl 1):i3-i6
  20. Koople JD, Zhu X, Lew NL, et al. Body weight-for-height relationships predict mortality in maintenance hemodialysis patients. Kidney Int. 1999;56:1136–1148
  21. Leavey SF, McCullough K, Hecking E, et al. Body mass index and mortality in “healthier” as compared with “sicker” hemodialysis patients: results from the Dialysis Outcomes and Practice Patterns Study (DOPPS). Nephrol Dial Transplant. 2001;16:2386–2394
  22. Chumlea WC. Anthropometric and body composition assessment in dialysis patients. Semin Dial. 2004;17:466–470
  23. Cano N, Di Costanzo-Dufetel J, Calaf R, et al. Prealbumin-retinol-binding-protein-retinol complex in hemodialysis patients. Am J Clin Nutr. 1988;47:664–667
  24. Cano NJ. Metabolism and clinical interest of serum transthyretin (prealbumin) in dialysis patients. Clin Chem Lab Med. 2002;40:1313–1319
  25. Ingenbleek Y, Young V. Significance of transthyretin in protein metabolism. Clin Chem Lab Med. 2002;40:1281–1291
  26. Pupim LB, Caglar K, Hakim RM, et al. Uremic malnutrition is a predictor of death independent of inflammatory status. Kidney Int. 2004;66:2054-2060
  27. Perunicic-Pekovic GB, Rasic ZR, Pljesa SI, et al. Effect of n-3 fatty acids on nutritional status and inflammatory markers in hemodialysis patients. Nephrology. 2007;12:331–336
  28. Tonbul HZ, Demir M, Altintepe L, et al. Malnutrition-inflammation-atherosclerosis (MIA) syndrome components in hemodialysis and peritoneal dialysis patients. Ren Fail. 2006;28:287–294
  29. Van Den Ham ECH, Kooman JP, Christiaans MHL, et al. Weight changes after renal transplantation: a comparison between patients on 5-mg maintenance steroid therapy and those on steroid-free immunosuppressive therapy. Transplant Int. 2003;16:300–306
  30. Chertow GM, Ackert K, Lew NL, et al. Prealbumin is an important as albumin in the nutritional assessment of hemodialysis patients. Kidney Int. 2000;58:2512–2517
  31. Ingenbleek Y, Young VR. Significance of transthyretin in protein metabolism. Clin Chem Lab Med. 2002;40:1281–1291
  32. Ponticelli C. Can we improve the results and increase the number of renal transplant?. Nephrol Dial Transplant. 1999;14(Suppl 3):10–14
  33. Kuszajewski ML, Clontz AS. Prealbumin is best for nutritional monitoring. Nursing. 2005;35:70–71

PII: S1051-2276(09)00102-2

doi: 10.1053/j.jrn.2009.04.001

Journal of Renal Nutrition
Volume 20, Issue 1 , Pages 44-51 , January 2010

Article Tools