Journal of Renal Nutrition
Volume 20, Issue 1 , Pages 17-22 , January 2010

Serum Retinol, Retinol-Binding Protein, and Transthyretin in Children Receiving Dialysis

  • Nancy Fassinger, PhD, RD

      Affiliations

    • Department of Nutrition and Food Science, Wayne State University, Detroit, Michigan
    • Children's Hospital of Michigan and Department of Pediatrics, Wayne State University, Detroit, Michigan
    • Corresponding Author InformationAddress reprint requests to Nancy Fassinger, PhD, RD, Children's Hospital of Michigan, 3901 Beaubien, Detroit, MI 48201.
    • ,
  • Abubakr Imam, MD

      Affiliations

    • Children's Hospital of Michigan and Department of Pediatrics, Wayne State University, Detroit, Michigan
    • ,
  • David M. Klurfeld, PhD

      Affiliations

    • Department of Nutrition and Food Science, Wayne State University, Detroit, Michigan

References 

  1. Werb R, Clark WF, Lindsay RM, et al. Serum vitamin A levels and associated abnormalities in patients on regular dialysis treatment. Clin Nephrol. 1979;12:63–68
  2. Blumberg A, Hanck A, Sander G. Vitamin nutrition in patients on continuous ambulatory peritoneal dialysis (CAPD). Clin Nephrol. 1983;20:244–250
  3. Farrington K, Miller P, Varghese Z, et al. Vitamin A toxicity and hypercalcaemia in chronic renal failure. Br Med J [Clin Res]. 1981;282:1999–2002
  4. Stewart WK, Fleming LW. Plasma retinol and retinol binding protein concentrations in patients on maintenance haemodialysis with and without vitamin A supplements. Nephron. 1982;30:15–21
  5. Vahlquist A, Berne B, Berne C. Skin content and plasma transport of vitamin A and beta-carotene in chronic renal failure. Eur J Clin Invest. 1982;12:63–67
  6. Cundy T, Earnshaw M, Heynen G, et al. Vitamin A and hyperparathyroid bone disease in uremia. Am J Clin Nutr. 1983;38:914–920
  7. Kriley M, Warady BA. Vitamin status of pediatric patients receiving long-term peritoneal dialysis. Am J Clin Nutr. 1991;53:1476–1479
  8. Zwolinska D, Grzeszczak W, Szczepanska M, et al. Lipid peroxidation and antioxidant enzymes in children on maintenance dialysis. Pediatr Nephrol. 2006;21:705–710
  9. Pilch S. Analysis of vitamin A data from the health and nutrition examination surveys. J Nutr. 1987;117:636–640
  10. Marshall WA, Tanner JM. Variations in pattern of pubertal changes in girls. Arch Dis Child. 1969;44:291–303
  11. Kelleher J, Humphrey CS, Homer D, et al. Vitamin A and its transport proteins in patients with chronic renal failure receiving maintenance haemodialysis and after renal transplantation. Clin Sci. 1983;65:619–626
  12. Stein G, Schone S, Geinitz D, et al. No tissue level abnormality of vitamin A concentration despite elevated serum vitamin A of uremic patients. Clin Nephrol. 1986;25:87–93
  13. Dong D, Ruuska SE, Levinthal DJ, et al. Distinct roles for cellular retinoic acid-binding proteins I and II in regulating signaling by retinoic acid. J Biol Chem. 1999;274:23695–23698
  14. Noy N. Retinoid-binding proteins: mediators of retinoid action. Biochem J. 2000;348:481–495
  15. Sundaram M, Sivaprasadarao A, DeSousa MM, et al. The transfer of retinol from serum retinol-binding protein to cellular retinol-binding protein is mediated by a membrane receptor. J Biol Chem. 1998;273:3336–3342
  16. Vieira AV, Schneider WJ, Vieira PM. Retinoids: transport, metabolism, and mechanisms of action. J Endocrinol. 1995;146:201–207
  17. Rashid R, Neill E, Maxwell H, et al. Growth and body composition in children with chronic kidney disease. Br J Nutr. 2007;97:232–238
  18. National Kidney Foundation-Dialysis Outcomes Quality Initiative . NKF-DOQI clinical practice guidelines for the treatment of anemia of chronic renal failure. Am J Kidney Dis. 1997;30(Suppl):S192–S240
  19. Kelleher J, Humphrey CS, Homer D, Davison AM, Giles GR, Losowsky MS. Vitamin A and its transport proteins in patients with chronic renal failure receiving maintenance haemodialysis and after renal transplantation. Clin Sci (Lond). 1983;65:619–626
  20. Stein G, Schone S, Geinitz D, et al. No tissue level abnormality of vitamin A concentration despite elevated serum vitamin A of uremic patients. Clin Nephrol. 1986;25:87–93
  21. Mydlik M, Derzsiova K, Valek A, Szabo T, Dandar V, Takac M. Vitamins and continuous ambulatory peritoneal dialysis (CAPD). Int Urol Nephrol. 1985;17:281–286
  22. Vahlquist A, Berne B, Danielson BG, Grefberg N, Berne C. Vitamin A losses during continuous ambulatory peritoneal dialysis. Nephron. 1985;41:179–183
  23. Delacoux E, Evstigneeff T, Leclercq M, et al. Skin disorders and vitamin A metabolism disturbances in chronic dialysis patients: the role of zinc, retinol-binding protein, retinol and retinoic acid. Clin Chim Acta. 1984;137:283–289
  24. Vannucchi MT, Vannucchi H, Humphreys M. Serum levels of vitamin A and retinol binding protein in chronic renal patients treated by continuous ambulatorial peritoneal dialysis. Int J Vitam Nutr Res. 1992;62:107–112

 A.I. is presently at the Children's Hospital Medical Center of Akron, Akron, Ohio.

 D.M.K. is presently at the Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland.

PII: S1051-2276(09)00137-X

doi: 10.1053/j.jrn.2009.05.005

Journal of Renal Nutrition
Volume 20, Issue 1 , Pages 17-22 , January 2010

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