Journal of Renal Nutrition
Volume 20, Issue 6 , Pages 384-391 , November 2010

Confounding Effect of Comorbidities and Malnutrition on Survival of Peritoneal Dialysis Patients

  • Narayan Prasad, DM

      Affiliations

    • Department of Nephrology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    • Corresponding Author InformationAddress reprint requests to Narayan Prasad, DM, Department of Nephrology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareli Road, Lucknow, Uttar Pradesh 226014, India.
    • ,
  • Amit Gupta, DNB

      Affiliations

    • Department of Nephrology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    • ,
  • Archana Sinha, MSc

      Affiliations

    • Department of Dietetics, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    • ,
  • Raj Kumar Sharma, DNB

      Affiliations

    • Department of Nephrology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    • ,
  • Anita Saxena, PhD

      Affiliations

    • Department of Nephrology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    • ,
  • Anupama Kaul, DM

      Affiliations

    • Department of Nephrology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    • ,
  • Dharmender Bhaduria, MD

      Affiliations

    • Department of Nephrology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    • ,
  • Anurag Gupta, MD

      Affiliations

    • Department of Nephrology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India

References 

  1. Paniagua R, Amato D, Vonesh E, et al. Effects of increased peritoneal clearances on mortality rates in peritoneal dialysis: ADEMEX, a prospective, randomized, controlled trial. J Am Soc Nephrol. 2002;13:1307–1320
  2. HEMO Study Group. Effect of dialysis dose and membrane flux in maintenance hemodialysis. N Engl J Med. 2002;347:2010–2019
  3. Canada-USA (CANUSA) Peritoneal Dialysis Study Group. Adequacy of dialysis and nutrition in continuous peritoneal dialysis: Association with clinical outcome. J Am Soc Nephrol. 1996;7:198–207
  4. Chung SH, Lindholm B, Lee HB. Influence of initial nutritional status on continuous ambulatory peritoneal dialysis patient survival. Perit Dial Int. 2000;20:19–26
  5. Bergström J. Nutrition and mortality in hemodialysis. J Am Soc Nephrol. 1995;6:1329–1341
  6. Prasad N, Gupta A, Sinha A, et al. Changes in nutritional status on follow-up of an incident cohort of continuous ambulatory peritoneal dialysis patients. J Ren Nutr. 2008;18:195–201
  7. Prasad N, Gupta A, Sinha A, et al. Impact of stratification of comorbidities on nutrition indices and survival in patients on continuous ambulatory peritoneal dialysis. Perit Dial Int. 2009;29(Suppl 2):S147–S151
  8. Bergström J. Why are dialysis patients malnourished?. Am J Kidney Dis. 1995;26:229–241
  9. Stenvinkel P, Heimbürger O, Lindholm B, et al. Are there two types of malnutrition in chronic renal failure? Evidence for relationships between malnutrition, inflammation and atherosclerosis (MIA syndrome). Nephrol Dial Transplant. 2000;15:953–960
  10. Bergström J, Lindholm B. Malnutrition, cardiac disease, and mortality: An integrated point of view. Am J Kidney Dis. 1998;32:834–841
  11. Foley RN, Parfrey PS, Harnett JD, et al. Hypoalbuminemia, cardiac morbidity, and mortality in end-stage renal disease. J Am Soc Nephrol. 1996;7:728–736
  12. Chung HS, Lindholm B, Lee BH. Is malnutrition an independent predictor of mortality in peritoneal dialysis patients?. Nephrol Dial Transplant. 2003;18:2134–2140
  13. Davies SJ, Phillips L, Naish PF, et al. Quantifying comorbidity in peritoneal dialysis patients and its relationship to other predictors of survival. Nephrol Dial Transplant. 2002;17:1085–1092
  14. Enia G, Sicuso C, Alati G, et al. Subjective global assessment in dialysis patients. Nephrol Dial Transplant. 1993;8:1094–1098
  15. Davies SJ, Russell L, Bryan J, et al. Comorbidity, urea kinetics, and appetite in continuous ambulatory peritoneal dialysis patients: Their interrelationship and prediction of survival. Am J Kidney Dis. 1995;26:353–361
  16. Abraham G, Varsha P, Mathew M, et al. Malnutrition and nutritional therapy of chronic kidney disease in developing countries: The Asian perspective. Adv Ren Replace Ther. 2003;10:213–221
  17. Heimbürger O, Qureshi AR, Blaner WS, et al. Hand-grip muscle strength, lean body mass, and plasma proteins as markers of nutritional status in patients with chronic renal failure close to start of dialysis therapy. Am J Kidney Dis. 2000;36:1213–1225
  18. Struijk DG, Krediet RT, Koomen GC, Boeschoten EW, Arisz L. The effect of serum albumin at the start of continuous ambulatory peritoneal dialysis treatment on patient survival. Perit Dial Int. 1994;14:121–126
  19. Kopple JD. Pathophysiology of protein-energy wasting in chronic renal failure. J Nutr. 1999;129(Suppl 1):247S–251S
  20. Chung SH, Chu WS, Lee HA, et al. Peritoneal transport characteristics, comorbid diseases and survival in CAPD patients. Perit Dial Int. 2000;20:541–547
  21. Cueto-Manzano AM, Correa-Rotter R. Is high peritoneal transport rate an independent risk factor for CAPD mortality?. Kidney Int. 2000;57:314–320
  22. Agarwal DK, Sharma AP, Gupta A, et al. Peritoneal equilibration test in Indian patients on continuous ambulatory peritoneal dialysis: Does it affect patient outcome?. Adv Perit Dial. 2000;16:148–151

PII: S1051-2276(10)00002-6

doi: 10.1053/j.jrn.2010.01.001

Journal of Renal Nutrition
Volume 20, Issue 6 , Pages 384-391 , November 2010

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