Journal of Renal Nutrition
Volume 20, Issue 6 , Pages 392-397 , November 2010

One-Year Serum Albumin is an Independent Predictor of Outcomes in Kidney Transplant Recipients

  • Rebecca Dahlberg, MD

      Affiliations

    • Department of Medicine, University of Wisconsin Madison SMPH, Madison, Wisconsin
    • ,
  • Brenda Muth, ARNP

      Affiliations

    • Department of Medicine, University of Wisconsin Madison SMPH, Madison, Wisconsin
    • ,
  • Milagros Samaniego, MD

      Affiliations

    • University of Michigan, Ann Arbor, Michigan
    • ,
  • R. Michael Hofmann, MD

      Affiliations

    • Department of Medicine, University of Wisconsin Madison SMPH, Madison, Wisconsin
    • ,
  • John Pirsch, MD

      Affiliations

    • Department of Medicine, University of Wisconsin Madison SMPH, Madison, Wisconsin
    • Department of Surgery, University of Wisconsin Madison SMPH, Madison, Wisconsin
    • ,
  • Arjang Djamali, MD

      Affiliations

    • Department of Medicine, University of Wisconsin Madison SMPH, Madison, Wisconsin
    • Department of Surgery, University of Wisconsin Madison SMPH, Madison, Wisconsin
    • Corresponding Author InformationAddress reprint requests to Arjang Djamali, MD, H4/564 Clinical Science Center, 600 Highland Avenue, Madison, Wisconsin 53792.

References 

  1. Hermann FR, Safran C, Levkoff SE, et al. Serum albumin level on admission as a predictor of death, length of stay, and readmission. Arch Intern Med. 1992;152:125–130
  2. Philips A, Shaper AG, Whincup PH. Association between serum albumin and mortality from cardiovascular disease, cancer and other causes. Lancet. 1989;2:1434–1436
  3. Quinlan GJ, Martin GF, Evans TW. Albumin: biochemical properties and therapeutic potential. Hepatology. 2005;41:1211–1219
  4. Parekh RS, Plantinga LC, Kao WH, et al. The association of sudden cardiac death with inflammation and other traditional risk factors. Kidney Int. 2008;74:1335–1342
  5. Franch-Arcas G. The meaning of hypoalbuminaemia in clinical practice. Clin Nutr. 2001;20:265–269
  6. Kaysen GA, Chertow GM, Adhikarla R, et al. Inflammation and reduced albumin synthesis associated with stable decline in serum albumin in hemodialysis patients. Kidney Int. 2004;65:1408–1415
  7. Menon V, Greene T, Wang X, et al. C-reactive protein and albumin as predictors of all-cause and cardiovascular mortality in chronic kidney disease. Kidney Int. 2005;68:766–772
  8. Iseki K, Kawazoe N, Fukiyama K. Serum albumin is a strong predictor of death in chronic dialysis patients. Kidney Int. 1993;44:115–119
  9. Ayus JF, Achinger SG. At the peril of dialysis patients: ignoring the failed transplant. Semin Dial. 2005;18:180–184
  10. Guijarro C, Massy ZA, Wiederkehr MR, et al. Serum albumin and mortality after renal transplantation. Am J Kidney Dis. 1996;24:117–123
  11. Becker BN, Becker YT, Heisey DM, et al. The impact of hypoalbuminemia in kidney-pancreas transplant recipients. Transplantation. 1999;68:72–75
  12. Levy AS, Coresch J, Greene T, et al. Using standardized serum creatinine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate. Ann Intern Med. 2006;145:247–254
  13. Wolfe RA, Ashby VB, Milford EL, et al. Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant. N Engl J Med. 1999;341:1725–1730
  14. Djamali A, Kendziorski C, Brazy PC, et al. Disease progression and outcomes in chronic kidney disease and renal transplantation. Kidney Int. 2003;64:1800–1807
  15. Kukla A, Adulla M, Pascual J, et al. CKD stage-to-stage progression in native and transplant kidney disease. Nephrol Dial Transplant. 2008;23:693–700

 Parts of this work were supported by NIH grants DK 067981-05, DK 070243-04 and the American Society of Nephrology-American Society of Transplantation John Merrill Award 2008-2010 (AD).

PII: S1051-2276(10)00079-8

doi: 10.1053/j.jrn.2010.03.008

Journal of Renal Nutrition
Volume 20, Issue 6 , Pages 392-397 , November 2010

Article Tools

* Image Usage & Resolution