| Special Report |
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Nephrology and Nutrition Leaders Coming to Hawaii for the World Renal Nutrition Week: Why is the 16th Congress in Renal Nutrition and Metabolism in Honolulu, Hawai’i, June 2012, Worth Attending?
RECENT ADVANCES IN our understanding of, and approach to, caring for patients with kidney disease and their nutritional and dietary management are expected to have unprecedented impact on the current ...
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Kamyar Kalantar-Zadeh,
Jerrilynn D. Burrowes,
Harold Franch,
Lisa A. Gutekunst,
T. Alp Ikizler,
Kunitoshi Iseki,
Yong-Lim Kim,
Christopher Wanner
et al.
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1-3
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| Original Research |
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Risk Factors for Hypovitaminosis D in Nondialyzed Chronic Kidney Disease Patients
09 June 2011
Background: Hypovitaminosis D is highly prevalent among patients with chronic kidney disease and has been associated with worse outcome even in the earlier stages of the disease. Objective: This study...
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Vilani Figuiredo-Dias,
Lilian Cuppari,
Miriam Ghedini Garcia-Lopes,
Aluízio Barbosa de Carvalho,
Sergio Antonio Draibe,
Maria Ayako Kamimura
et al.
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4-11
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Persistent Homocysteine Metabolism Abnormality Accelerates Cardiovascular Disease in Hemodialyzed Patients—the Nishinomiya Study
13 July 2011
Objective: Homocysteine (Hcy) is an intermediate in sulfur amino acid metabolism and may induce oxidative stress. Several studies have reported that elevated Hcy in end-stage renal failure may contrib...
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Yukiko Hasuike,
Yasue Hama,
Hiroshi Nonoguchi,
Kahori Hori,
Masanori Tokuyama,
Kazuhiro Toyoda,
Satoshi Hazeki,
Masayoshi Nanami,
Yoshinaga Otaki,
Takahiro Kuragano,
Takeshi Nakanishi
et al.
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12-18.e1
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Daily Magnesium Intake and Hypermagnesemia in Hemodialysis Patients With Chronic Kidney Disease
27 May 2011
Objective: The aim of this study was to evaluate daily magnesium intake and the relation to its serum concentration in hemodialysis (HD) patients with chronic kidney disease (CKD). Design: This is a p...
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Katarzyna Wyskida,
Joanna Witkowicz,
Jerzy Chudek,
Andrzej Więcek
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19-26
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Relationship Between Appetite and Symptoms of Depression and Anxiety in Patients on Chronic Hemodialysis
20 June 2011
Objective: We aimed at evaluating the association between appetite and symptoms of depression and anxiety, cognitive dysfunction, fatigue, and comorbidities in patients on hemodialysis (HD). Design: A...
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Maurizio Bossola,
Claudia Ciciarelli,
Enrico Di Stasio,
Nicola Panocchia,
Gian Luigi Conte,
Fausto Rosa,
Antonio Tortorelli,
Giovanna Luciani,
Luigi Tazza
et al.
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27-33
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Converting to Doxercalciferol Capsules From Intravenous Paricalcitol or Doxercalciferol
09 June 2011
Objective: The purpose of the 2 studies presented in this article was to determine the clinically appropriate dose of doxercalciferol capsules that is required to maintain similar intact parathyroid h...
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K. Shashi Kant,
Alejandro R. Gonzalez,
Srinivas Hariachar,
Marializa Bernardo,
Ajay Duggal,
Sara Engstrand,
John Hunter,
Melissa Plone,
Joachim Hertel
et al.
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34-40.e2
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Interdialytic Weight Gain Does Not Influence the Nutrition of New Hemodialysis Patients
27 May 2011
Objective: The aim of the present study was to assess the relationship between interdialytic weight gain (IDWG) and nutrition markers in hemodialysis (HD) patients, by means of repeated measures analy...
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Yu-Wei Chen,
Han-Hsiang Chen,
Chi-Feng Pan,
Chiung-Ying Chang,
Chih-Jen Wu
et al.
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41-49
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| Research Briefs |
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Oral Supplementation of Turmeric Decreases Proteinuria, Hematuria, and Systolic Blood Pressure in Patients Suffering From Relapsing or Refractory Lupus Nephritis: A Randomized and Placebo-controlled Study
11 July 2011
Objective: Despite highly expensive treatments, lupus nephritis remains a major cause of morbidity and mortality in patients with relapsing or refractory lupus nephritis. Meanwhile, experimental studi...
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Parviz Khajehdehi,
Batol Zanjaninejad,
Elham Aflaki,
MohamadAli Nazarinia,
Fariborz Azad,
Leila Malekmakan,
Gholam-Reza Dehghanzadeh
et al.
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50-57
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Association Between Vascular Calcification Scores on Plain Radiographs and Fatty Acid Contents of Erythrocyte Membrane in Hemodialysis Patients
27 May 2011
Objective: Vascular calcification (VC) scores determined by using simple plain radiographic films are known to be associated with coronary artery disease and mortality in patients undergoing hemodialy...
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Young K. Son,
Su M. Lee,
Seong E. Kim,
Ki H. Kim,
Seon Y. Lee,
Hae R. Bae,
Jin Y. Han,
Yongsoon Park,
Won S. An
et al.
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58-66
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Seasonal Changes in Phosphorus Content of Fish Tissue as They Relate to Diets of Renal Patients
11 July 2011
Objective: To investigate seasonal variations in tissue phosphorus (P) levels, P to protein ratio, and P to omega-3 fatty acid (ω3-FA) ratio in 2 species of fish that are commonly consumed in Lebanon....
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Sana Ghaddar,
I. Patrick Saoud
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67-71
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| Message From the Chairperson |
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Call to Arms…
MY FELLOW RENAL dietitian, if ever there was a time to stand up, make noise, and be heard, it is now. We as renal healthcare professionals can no longer sit by in the wings as Medicare and dialysis un...
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Lisa Gutekunst
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72-74
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| Announcements |
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January 2012 Meeting Announcements
February 14-17, 2012 17th Continuous Renal Replacement Therapies (CRRT) Conference, Sans Diego, California. Visit www.crrtonline.comor call 858-272-1018.
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75
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| Patient Education |
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Nutrition Supplementation and Chronic Kidney Disease: What Are the Options?
LOW SERUM ALBUMIN and low protein intake are independently associated with increased risk of mortality in the hemodialysis and peritoneal dialysis populations. In a hypothetical theoretical model, int...
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Amy Braglia Tarpey
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e1-e2
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| Product Update |
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Medication Reminder Systems: An Adjunct Technique in Improving Phosphate Binder Adherence
IT IS A known fact that hyperphosphatemia is one of the risk factors for cardiovascular disease among patients with chronic kidney disease (CKD). According to the Kidney Disease Outcome and Quality In...
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Thessa Obrero Churillo
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e3-e9
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| Proceedings of the 7th International Congress on Uremia Research and Toxicity |
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Uremia Research and Toxicity
We are pleased to provide the readers of the Journal of Renal Nutrition with the Proceedings of the Seventh International Congress on Uremia Research and Toxicity, which was held in Nagoya, Japan on M...
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Shaul G. Massry,
Toshimitsu Niwa,
Boleslaw Rutkowski
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76
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Dysregulated Oxygen Metabolism of the Kidney by Uremic Toxins: Review
Because kidneys consume a large amount of oxygen and are relatively inefficient in oxygen uptake, they are susceptible to hypoxia, especially in patients with advanced chronic kidney disease accompani...
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Chih-Kang Chiang,
Tetsuhiro Tanaka,
Masaomi Nangaku
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77-80
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Adipokines as Uremic Toxins
The adipose tissue has pleiotropic functions far beyond the mere storage of energy, and it secretes a number of hormones and cytokines, called adipokines, which have biological effects that impact hea...
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Daniel Teta
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81-85
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Indoxyl Sulfate Induces Endothelial Cell Senescence by Increasing Reactive Oxygen Species Production and p53 Activity
Background/Aim: We have reported that indoxyl sulfate (IS), a uremic toxin, accelerates proximal tubular cell senescence. Asymmetric dimethylarginine (ADMA), an inhibitor of nitric oxide synthase, has...
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Yelixiati Adelibieke,
Hidehisa Shimizu,
Gulinuer Muteliefu,
Dilinaer Bolati,
Toshimitsu Niwa
et al.
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86-89
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An Update on Protein-Bound Uremic Retention Solutes
Although protein-bound uremic retention solutes are recognized as 1 of the 3 main categories of uremic retention solutes, they only recently have been submitted to thorough analysis. In vitro and ex v...
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Raymond Vanholder,
Eva Schepers,
Anneleen Pletinck,
Nathalie Neirynck,
Griet Glorieux
et al.
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90-94
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Cellular Toxicity of Nicotinamide Metabolites
There are almost 100 different substances called uremic toxins. Nicotinamide derivatives are known as new family of uremic toxins. These uremic compounds play a role in an increased oxidative stress a...
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Bolesław Rutkowski,
Przemysław Rutkowski,
Ewa Słomińska,
Ryszard T. Smolenski,
Julian Świerczyński
et al.
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95-97
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Role of Uremic Toxins and Oxidative Stress in the Development of Chronic Kidney Disease–Mineral and Bone Disorder
The kidney plays an important role in the regulation of mineral metabolism. As kidney function declines, there is a progressive deterioration in mineral homeostasis, along with various abnormalities, ...
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Hisae Tanaka,
Hirotaka Komaba,
Masahiro Koizumi,
Takatoshi Kakuta,
Masafumi Fukagawa
et al.
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98-101
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Indoxyl Sulfate Induces Nephrovascular Senescence
Indoxyl sulfate is markedly accumulated in the serum of chronic kidney disease (CKD) patients. The oral sorbent AST-120 reduces serum levels of indoxyl sulfate in CKD patients by adsorbing indole, a p...
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Toshimitsu Niwa,
Hidehisa Shimizu
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102-106
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A Nexus of Progression of Chronic Kidney Disease: Tryptophan, Profibrotic Cytokines, and Charcoal
Fibrosis plays a major role in the pathogenesis of progressive chronic kidney disease (CKD). The inhibition of the renin-angiotensin system, which promotes fibrosis, has become the standard of care in...
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Gerald Schulman
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107-113
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SIRTUIN 1 Gene Polymorphisms are Associated With Cholesterol Metabolism and Coronary Artery Calcification in Japanese Hemodialysis Patients
Objectives: Sirtuin 1 (SIRT1), a longevity gene, protects cells against oxidative and genotoxic stress. This study aimed to investigate the association of SIRT 1 gene single-nucleotide polymorphisms, ...
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Yasuhiko Shimoyama,
Yoko Mitsuda,
Yoshinari Tsuruta,
Koji Suzuki,
Nobuyuki Hamajima,
Toshimitsu Niwa
et al.
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114-119
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Cardiovascular Biomarkers in Chronic Kidney Disease
Cardiovascular disease (CVD) is the major cause of death in patients with advanced chronic kidney disease (CKD). Recent studies have suggested that novel risk factors, uremia- or dialysis-related, are...
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Sun-Hee Park,
Peter Stenvinkel,
Bengt Lindholm
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120-127
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AGEs and Cardiovascular Diseases in Patients With End-Stage Renal Diseases
Cardiovascular disease is the major cause of death in patients with renal insufficiency, accounting for 50% of all deaths in renal replacement therapy patients. Mortality from cardiovascular diseases ...
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Yoshiki Nishizawa,
Hidenori Koyama,
Masaaki Inaba
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128-133
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Carbamylated Low-Density Lipoprotein: Nontraditional Risk Factor for Cardiovascular Events in Patients With Chronic Kidney Disease
The high cardiovascular morbidity and mortality associated with chronic kidney disease (CKD) cannot be explained entirely by traditional risk factors. Urea spontaneously dissociates to form cyanate, w...
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Eugene O. Apostolov,
Alexei G. Basnakian,
Ercan Ok,
Sudhir V. Shah
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134-138
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Coronary Artery Calcification Score is Associated With Mortality in Japanese Hemodialysis Patients
Objective: Coronary artery calcification has been associated with higher mortality in coronary artery disease and chronic kidney disease. This study aimed to correlate coronary artery calcification sc...
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Yasuhiko Shimoyama,
Yoshinari Tsuruta,
Toshimitsu Niwa
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139-142
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Advanced Oxidation Protein Products and Advanced Glycation End Products in Children and Adolescents With Chronic Renal Insufficiency
Objective: Advanced oxidation protein products (AOPPs) represent dityrosine-containing cross-linked protein modifications formed mainly via myeloperoxidase reaction, supposed to accelerate the uremia-...
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Katarína Šebeková,
Kristína Klenovicsová,
Juliana Ferenczová,
Juraj Hedvig,
L'udmila Podracká,
August Heidland
et al.
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143-148
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Effect of Uremia on Structure and Function of Immune System
End-stage renal disease (ESRD) is simultaneously associated with immune activation, marked by systemic inflammation, and immune deficiency. Systemic inflammation contributes to atherosclerosis, cardio...
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Nosratola D. Vaziri,
Madeleine V. Pahl,
Albert Crum,
Keith Norris
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149-156
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International Evaluation of Unrecognizably Uglifying Human Faces in Late and Severe Secondary Hyperparathyroidism in Chronic Kidney Disease. Sagliker Syndrome. A Unique Catastrophic Entity, Cytogenetic Studies for Chromosomal Abnormalities, Calcium-Sensing Receptor Gene and GNAS1 Mutations. Striking and Promising Missense Mutations on the GNAS1 Gene Exons 1, 4, 10, 4
Hypotheses explaining pathogenesis of secondary hyperparathyroidism (SH) in late and severe CKD as a unique entity called Sagliker syndrome (SS) are still unclear. This international study contains 60...
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Ismail Yildiz,
Yahya Sagliker,
Osman Demirhan,
Erdal Tunc,
Nihal Inandiklioglu,
Deniz Tasdemir,
Vidya Acharya,
Ling Zhang,
Ovidia Golea,
Alaa Sabry,
Dhananjay S. Ookalkar,
Cristina Capusa,
Dana Radulescu,
Liliana Garneata,
Gabriel Mircescu,
Hedi Ben Maiz,
Cheng Hsu Chen,
Jorge Prado Rome,
Mansour Benzegoutta,
Nuray Paylar,
Kamil Eyuboglu,
Ersin Karatepe,
Mustafa Esenturk,
Onder Yavascan,
Alicza Grzegorzevska,
Valery Shilo,
Mitra Mahdavi Mazdeh,
Ramos Carillo Francesco,
Zaghloul Gouda,
Siddik Momin Adam,
Idris Emir,
Faith Ocal,
Erol Usta,
Necati Kiralp,
Cemal Sagliker,
Piril Sagliker Ozkaynak,
Hasan Sabit Sagliker,
Mahmoud Bassuoni,
Oktay Sekin
et al.
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157-161
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New-Onset Posttransplant Diabetes Mellitus Begins in the Dialysis Period
Objectives: New-onset posttransplant diabetes mellitus (PTDM) affects >20% of transplant recipients at 1 year and is associated with increased risk of mortality. From the pathogenetic point of view...
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Katarzyna Madziarska,
Marian Klinger
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162-165
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Muscle and Fat Metabolism in Obesity After Kidney Transplantation: No Effect of Peritoneal Dialysis or Hemodialysis
Our prospective study analyzed selected adipocytokines: adiponectin (ADPN), leptin, visfatin, and asymmetric dimethylarginine (ADMA) in the plasma of renal transplant recipients previously treated by ...
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Vladimír Teplan,
Jan Malý,
Robert Gürlich,
Vladimír Teplan,
Michal Kudla,
Jan Pit'ha,
Jaroslav Racek,
Martin Haluzík,
Ladislav Šenolt,
Milena Štollová
et al.
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166-170
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Ghrelin and Muscle Metabolism in Chronic Uremia
Patients with chronic kidney disease (CKD) are prone to nutritional complications with negative prognostic impact. In particular, protein–energy wasting is a major CKD-associated clinical burden, and ...
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Rocco Barazzoni,
Gianluca Gortan Cappellari,
Michela Zanetti,
Gianfranco Guarnieri
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171-175
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AST-120 Ameliorates Epithelial-to-Mesenchymal Transition and Interstitial Fibrosis in the Kidneys of Chronic Kidney Disease Rats
Objective: Indoxyl sulfate (IS), a uremic toxin, is a risk factor for progression of chronic kidney disease (CKD). AST-120 reduces serum IS and delays the progression of CKD. This study aimed to exami...
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Dilinaer Bolati,
Hidehisa Shimizu,
Toshimitsu Niwa
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176-180
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Chemical and Physiological Relevance of Glucose Degradation Products in Peritoneal Dialysis
Fibrosis and vascular sclerosis are main complications that limit the long-term application of peritoneal dialysis (PD). Low biocompatibility has been largely attributed to the presence of glucose deg...
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Stefan Mittelmaier,
Toshimitsu Niwa,
Monika Pischetsrieder
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181-185
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A Brief Review of External Mass Balance and Internal Calcium Redistribution in Dialysis Patients—Is Calcium a Uremic Toxin?
Recent debates between 2 schools of thought on calcium mass balance in dialysis patients and its relevance to disease—one emphasizing external calcium mass balance, and the other, internal calcium red...
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Jochen G. Raimann,
Stephan Thijssen,
Nathan W. Levin
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186-190
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Hyperhomocysteinemia in Chronic Renal Failure: Alternative Therapeutic Strategies
Chronic renal failure and uremia represent states wherein high blood levels of homocysteine, a cardiovascular risk factor, are largely resistant to folate therapy. Indeed, normalization of homocystein...
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Alessandra F. Perna,
Immacolata Sepe,
Diana Lanza,
Rosa Maria Pollastro,
Natale G. De Santo,
Diego Ingrosso
et al.
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191-194
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Dietary and Synthetic Activators of the Antistress Gene Response in Treatment of Renal Disease
Renal failure is associated with increased vascular inflammation, oxidative stress and dicarbonyl stress linked to development of cardiovascular disease, and other complications. The endogenous defens...
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Paul J. Thornalley,
Naila Rabbani
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195-202
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The Removal of Protein-Bound Solutes by Dialysis
Protein-bound solutes that accumulate in plasma when the kidneys fail are poorly cleared by conventional dialysis. Means have been developed to reduce the levels of such solutes, either by modifying t...
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Timothy W. Meyer
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203-206
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Anxiety and Depression in Maintenance Dialysis Patients: Preliminary Data of a Cross-sectional Study and Brief Literature Review
Background: Anxiety and depression affect the quality of life of maintenance dialysis (MD) patients. There is little information concerning the extent to which the experience of individual hemodialysi...
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Usama Feroze,
David Martin,
Kamyar Kalantar-Zadeh,
Jun Chul Kim,
Astrid Reina-Patton,
Joel D. Kopple
et al.
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207-210
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Survival Is Not Enough
Survival is notenough is a yearly international event started in 2007 in Naples, Italy, in the week of the World Kidney Day to discuss the needs of renal patients and the quality of life of a category...
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Natale Gaspare De Santo,
Alessandra Perna,
Aziz El Matri,
Rosa Maria De Santo,
Massimo Cirillo
et al.
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211-219
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Masthead
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A1
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Editorial Board
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A2
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Table of Contents
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A3-A7
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Guidelines for Contributing Authors
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A8-A12
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